Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 2/20 | 0.47 |
| ▸ | IP6K3 | Q96PC2 | 2/20 | 0.47 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.47 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8173275 | 1.00 | IP6K1 (0.47) | IP6K1IP6K3IP6K2PLA2G4ACYP19A1 | |
| SCHEMBL8173584 | 0.85 | NR1H4 (0.43) | CYP19A1HDAC6HDAC1HDAC10HDAC2 | |
| SCHEMBL8173581 | 0.85 | NR1H4 (0.43) | CYP19A1HDAC6HDAC1HDAC10HDAC2 | |
| SCHEMBL8156486 | 0.84 | PTGER4 (0.55) | IP6K1CYP19A1HDAC6HDAC1HDAC10 | |
| SCHEMBL13170473 | 0.81 | KDM4E (0.61) | LMNAALDH1A1HTT | |
| SCHEMBL13170385 | 0.81 | KDM4E (0.61) | LMNAALDH1A1HTT | |
| SCHEMBL8495045 | 0.79 | ALDH1A1 (0.61) | CYP19A1HDAC6HDAC1HDAC10HDAC3 | |
| SCHEMBL10977143 | 0.78 | CYP19A1 (0.64) | CYP19A1HDAC6HDAC1HDAC10ALDH1A1 | |
| SCHEMBL10977145 | 0.78 | CYP19A1 (0.64) | CYP19A1HDAC6HDAC1HDAC10ALDH1A1 | |
| SCHEMBL8154947 | 0.77 | CYP19A1 (0.77) | CYP19A1HDAC6HDAC1HDAC10P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043247-A | A SUBSTITUTED ACRYLIC ACIDS FOR USE IN TREATMENT OF HUMAN AND ANIMAL DISORDERS, AND PURIFICATION OF PROTEINS OR GLYCOPROTEINS, AND TO THEIR USE IN DIAGNOSIS | NOVO NORDISK A/S (DK) | 2000-03-28 | — | — | US | claimed |
| WO-1997039748-A1 | MODULATORS OF MOLECULES WITH PHOSPHOTYROSINE RECOGNITION UNITS | NOVO NORDISK A/S (DK) | 1997-10-30 | — | — | WO | claimed |
| US-6043247-A | A SUBSTITUTED ACRYLIC ACIDS FOR USE IN TREATMENT OF HUMAN AND ANIMAL DISORDERS, AND PURIFICATION OF PROTEINS OR GLYCOPROTEINS, AND TO THEIR USE IN DIAGNOSIS | NOVO NORDISK A/S (DK) | 2000-03-28 | — | — | US | disclosed |