Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 17/20 | 0.60 |
| ▸ | DRD3 | P35462 | 7/20 | 0.60 |
| ▸ | HTR1A | P08908 | 5/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.60 |
| ▸ | HTR2A | P28223 | 5/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.60 |
| ▸ | HRH1 | P35367 | 5/20 | 0.60 |
| ▸ | HTR2B | P41595 | 5/20 | 0.60 |
| ▸ | DRD1 | P21728 | 4/20 | 0.60 |
| ▸ | DRD5 | P21918 | 4/20 | 0.60 |
| ▸ | HTR7 | P34969 | 4/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CCR1 | P32246 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8010420 | 0.87 | DRD2 (0.72) | DRD2DRD3HTR1ASLC6A2HTR2A | |
| SCHEMBL7665773 | 0.81 | DRD2 (0.65) | DRD2DRD3HTR1ASLC6A2HTR2A | |
| SCHEMBL8570792 | 0.81 | DRD2 (0.65) | DRD2DRD3HTR1ASLC6A2HTR2A | |
| Hydrochloric Acid SCHEMBL7658319 | 0.80 | DRD2 (0.64) | DRD2DRD3HTR1ASLC6A2HTR2A | |
| Hydrochloric Acid SCHEMBL7662807 | 0.80 | DRD2 (0.64) | DRD2DRD3HTR1ASLC6A2HTR2A | |
| SCHEMBL8049113 | 0.80 | DRD2 (0.56) | DRD2DRD3HTR1ASLC6A2HTR2A | |
| Hydrochloric Acid SCHEMBL11840393 | 0.80 | DRD2 (0.86) | DRD2DRD3HTR1ASLC6A2HTR2A | |
| SCHEMBL7665768 | 0.79 | DRD2 (0.66) | DRD2DRD3HTR1ASLC6A2HTR2A | |
| SCHEMBL9529535 | 0.78 | DRD2 (0.60) | DRD2DRD3HTR1ASLC6A2HTR2A | |
| Hydrochloric Acid SCHEMBL7658312 | 0.78 | DRD2 (0.64) | DRD2DRD3HTR1ASLC6A2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000027816-A1 | OXAZOLIDINONES USEFUL AS ALPHA 1A ADRENOCEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2000-05-18 | — | — | WO | claimed |
| WO-2000027816-A1 | OXAZOLIDINONES USEFUL AS ALPHA 1A ADRENOCEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2000-05-18 | — | — | WO | disclosed |