Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 15/20 | 0.65 |
| ▸ | DRD3 | P35462 | 7/20 | 0.62 |
| ▸ | HTR1A | P08908 | 5/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.62 |
| ▸ | HTR2A | P28223 | 5/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.62 |
| ▸ | HRH1 | P35367 | 5/20 | 0.62 |
| ▸ | HTR2B | P41595 | 5/20 | 0.62 |
| ▸ | DRD1 | P21728 | 4/20 | 0.62 |
| ▸ | DRD5 | P21918 | 4/20 | 0.62 |
| ▸ | HTR7 | P34969 | 4/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8010420 | 0.91 | DRD2 (0.72) | DRD2DRD3HTR1ASLC6A2HTR2A | |
| SCHEMBL7665773 | 0.85 | DRD2 (0.65) | DRD2DRD3HTR1ASLC6A2HTR2A | |
| SCHEMBL11938907 | 0.85 | DRD2 (0.65) | DRD2DRD3HTR1ASLC6A2HTR2A | |
| SCHEMBL11778752 | 0.84 | SIGMAR1 (0.70) | DRD2SIGMAR1LMNAOPRM1OPRK1 | |
| SCHEMBL8049113 | 0.84 | DRD2 (0.56) | DRD2DRD3HTR1ASLC6A2HTR2A | |
| Hydrochloric Acid SCHEMBL7662807 | 0.84 | DRD2 (0.64) | DRD2DRD3HTR1ASLC6A2HTR2A | |
| Hydrochloric Acid SCHEMBL7658319 | 0.84 | DRD2 (0.64) | DRD2DRD3HTR1ASLC6A2HTR2A | |
| SCHEMBL8173291 | 0.81 | DRD2 (0.60) | DRD2DRD3HTR1ASLC6A2HTR2A | |
| SCHEMBL20652864 | 0.80 | DRD2 (0.79) | DRD2DRD3HTR1ASLC6A2HTR2A | |
| SCHEMBL904900 | 0.80 | DRD2 (0.72) | DRD2DRD3HTR1ASLC6A2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837707-A | USEFUL IN TREATING ANXIETY, PSYCHOSIS, EPILEPSY, CONVULSIONS, AMNESIA, PARKINSON'S DISEASE | H. LUNDBECK A/S (DK) | 1998-11-17 | — | — | US | disclosed |
| US-5684012-A | TREATMENT OF PSYCHOLOGICAL AND NEUROLOGICAL DISORDERS | H. LUNDBECK A/S (DK) | 1997-11-04 | — | — | US | disclosed |