Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | HRH1 | P35367 | 3/20 | 0.44 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7604312 | 0.98 | LMNA (0.58) | LMNAALDH1A1DRD2HRH1SLC6A1 | |
| Oxalic Acid SCHEMBL8173667 | 0.91 | SLC6A1 (0.52) | LMNAALDH1A1SLC6A1 | |
| SCHEMBL8173413 | 0.90 | LMNA (0.53) | LMNAALDH1A1DRD2HRH1SLC6A1 | |
| SCHEMBL7604917 | 0.90 | SLC6A1 (0.53) | LMNAALDH1A1SLC6A1 | |
| Oxalic Acid SCHEMBL8173826 | 0.89 | LMNA (0.70) | LMNAALDH1A1DRD2HRH1SLC6A1 | |
| SCHEMBL8172078 | 0.89 | LMNA (0.53) | LMNAALDH1A1LTA4HKDM4EMAPT | |
| SCHEMBL7607300 | 0.87 | LMNA (0.72) | LMNAALDH1A1DRD2HRH1LTA4H | |
| SCHEMBL8173666 | 0.82 | LMNA (0.49) | LMNAALDH1A1SLC6A1KDM4E | |
| SCHEMBL8161721 | 0.82 | LMNA (0.49) | LMNAALDH1A1KDM4EMEN1MAPT | |
| Oxalic Acid SCHEMBL8161910 | 0.80 | LMNA (0.65) | LMNAALDH1A1SLC6A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060468-A | ANTIINFLAMMATORY AGENTS | NOVO NORDISK A/S (DK) | 2000-05-09 | — | — | US | disclosed |
| EP-0934314-A1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998015550-A1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-04-16 | — | — | WO | disclosed |