Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28709497 | 0.86 | CYP1A2 (0.40) | MTNR1AMTNR1BATMLMNACES2 | |
| SCHEMBL10454330 | 0.84 | MTNR1A (0.38) | MTNR1AMTNR1BLMNAAKT1MAPK1 | |
| SCHEMBL14729820 | 0.84 | MTNR1A (0.34) | MTNR1AMTNR1BLMNAAKT1MAPK1 | |
| SCHEMBL5513089 | 0.80 | ATM (0.43) | MTNR1AMTNR1BATMLMNACES2 | |
| SCHEMBL817341 | 0.80 | TSHR (0.35) | MTNR1AMTNR1BLMNACES2CES1 | |
| SCHEMBL4442135 | 0.80 | TSHR (0.35) | MTNR1AMTNR1BLMNACES2CES1 | |
| SCHEMBL5513078 | 0.80 | ATM (0.43) | MTNR1AMTNR1BATMLMNACES2 | |
| SCHEMBL5595601 | 0.80 | TSHR (0.35) | MTNR1AMTNR1BLMNACES2CES1 | |
| SCHEMBL5085213 | 0.79 | TSHR (0.43) | MTNR1AMTNR1BATMLMNACES2 | |
| SCHEMBL23152624 | 0.77 | ATM (0.36) | MTNR1AMTNR1BATMLMNACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906651-B2 | Catalytic system of asymmetric reactions in aqueous media; react a silicon enolate and formaldehyde; catalyst obtained by mixing chiral ligands with scandium triflate | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-03-15 | — | — | US | disclosed |
| US-20080269496-A1 | Method for Producing Optically Active Hydroxymethylated Compounds | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269496-A1 | Method for Producing Optically Active Hydroxymethylated Compounds | TET1, TET3, CYP3A4 | MTNR1A 3191/4885MTNR1B 2602/4885ATM 4254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.