Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | F12 | P00748 | 1/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | F3 | P13726 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CES2 | O00748 | 3/20 | 0.32 |
| ▸ | CES1 | P23141 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | C1S | P09871 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4442135 | 1.00 | TSHR (0.35) | TSHRF2F10F12F7 | |
| SCHEMBL5595601 | 1.00 | TSHR (0.35) | TSHRF2F10F12F7 | |
| SCHEMBL23152626 | 0.88 | SMN1; SMN2 (0.42) | LMNAALDH1A1MAPK1MAPTNPC1 | |
| SCHEMBL23152625 | 0.88 | SMN1; SMN2 (0.42) | LMNAALDH1A1MAPK1MAPTNPC1 | |
| SCHEMBL14471815 | 0.83 | CYP19A1 (0.34) | TSHRF2LMNATP53KMT2A | |
| SCHEMBL14471814 | 0.83 | CYP19A1 (0.34) | TSHRF2LMNATP53KMT2A | |
| SCHEMBL14471831 | 0.83 | CYP19A1 (0.34) | TSHRF2LMNATP53KMT2A | |
| SCHEMBL11412872 | 0.82 | AKR1C1 (0.41) | TSHRLMNAKMT2AALDH1A1MAPK1 | |
| SCHEMBL23152622 | 0.82 | AKR1C1 (0.41) | TSHRLMNAKMT2AALDH1A1MAPK1 | |
| SCHEMBL11412870 | 0.82 | AKR1C1 (0.41) | TSHRLMNAKMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809567-B2 | Method for producing silylenol ethers | KYOTO UNIVERSITY (JP) | 2014-08-19 | — | — | US | disclosed |
| US-8809567-B2 | Method for producing silylenol ethers | KYOTO UNIVERSITY (JP) | 2014-08-19 | — | — | US | disclosed |
| US-8809567-B2 | Method for producing silylenol ethers | KYOTO UNIVERSITY (JP) | 2014-08-19 | — | — | US | disclosed |
| EP-2545991-B1 | GOLD POLYMER NANO-STRUCTURE-SUPPORTED SCANDIUM CATALYST AND USE OF THE SAME | JAPAN SCIENCE & TECH AGENCY (JP) | 2014-06-04 | — | — | EP | disclosed |
| US-8735522-B2 | Gold-polymer nanostructure-immobilized scandium catalyst and its use | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2014-05-27 | — | — | US | disclosed |
| US-8735522-B2 | Gold-polymer nanostructure-immobilized scandium catalyst and its use | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2014-05-27 | — | — | US | disclosed |
| US-20130059999-A1 | GOLD-POLYMER NANOSTRUCTURE-IMMOBILIZED SCANDIUM CATALYST AND ITS USE | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2013-03-07 | — | — | US | disclosed |
| US-20130053567-A1 | METHOD FOR PRODUCING SILYLENOL ETHERS | KYOTO UNIVERSITY (JP) | 2013-02-28 | — | — | US | disclosed |
| US-20130053567-A1 | METHOD FOR PRODUCING SILYLENOL ETHERS | KYOTO UNIVERSITY (JP) | 2013-02-28 | — | — | US | disclosed |
| US-20130053567-A1 | METHOD FOR PRODUCING SILYLENOL ETHERS | KYOTO UNIVERSITY (JP) | 2013-02-28 | — | — | US | disclosed |
| EP-2543674-A1 | METHOD FOR PRODUCING SILYLENOL ETHERS | Kyoto University (JP) | 2013-01-09 | — | — | EP | disclosed |
| EP-2543674-A1 | METHOD FOR PRODUCING SILYLENOL ETHERS | Kyoto University (JP) | 2013-01-09 | — | — | EP | disclosed |
| US-7906651-B2 | Catalytic system of asymmetric reactions in aqueous media; react a silicon enolate and formaldehyde; catalyst obtained by mixing chiral ligands with scandium triflate | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-03-15 | — | — | US | disclosed |
| US-7541307-B2 | Method for manufacturing an optically active hydroxymethylated compound and a catalyst therefore | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2009-06-02 | — | — | US | disclosed |
| US-20080269496-A1 | Method for Producing Optically Active Hydroxymethylated Compounds | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-10-30 | — | — | US | disclosed |
| US-20080139835-A1 | Method for Manufacturing an Optically Active Hydroxymethylated Compound and a Catalyst Therefore | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-06-12 | — | — | US | disclosed |
| US-7323603-B2 | Reacting an aldehyde with a silyl enol ether in an aqueous medium in the presence of a boronic acid, a surfactant, and a Bronsted acid | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2008-01-29 | — | — | US | disclosed |
| US-20070238902-A1 | Method for Performing Aldol Reaction in Water | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2007-10-11 | — | — | US | disclosed |
| US-7235698-B2 | Enantioselective, catalytic allylation of ketones and olefins | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-06-26 | — | — | US | disclosed |
| US-7235698-B2 | Enantioselective, catalytic allylation of ketones and olefins | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139835-A1 | Method for Manufacturing an Optically Active Hydroxymethylated Compound and a Catalyst Therefore | OGFOD1, POF1B, EEF1D | TSHR 1298/4885F2 249/4885F10 521/4885 |
| US-20080269496-A1 | Method for Producing Optically Active Hydroxymethylated Compounds | TET1, TET3, CYP3A4 | TSHR 3982/4885F2 2040/4885F10 3591/4885 |
| US-20130059999-A1 | GOLD-POLYMER NANOSTRUCTURE-IMMOBILIZED SCANDIUM CATALYST AND ITS USE | SCLY, SPIN3, ACSL3 | TSHR 1100/4885F2 632/4885F10 1796/4885 |
| US-20130053567-A1 | METHOD FOR PRODUCING SILYLENOL ETHERS | AKR7A2, MSMO1, CYP2E1 | TSHR 4458/4885F2 713/4885F10 1526/4885 |
| US-20070238902-A1 | Method for Performing Aldol Reaction in Water | AKR1C3, ADH1C, ADH5 | TSHR 850/4885F2 198/4885F10 1038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.