Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | DTYMK | P23919 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TPMT | P51580 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8173577 | 0.94 | SIRT6 (0.45) | SIRT6PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL8163022 | 0.91 | TDP1 (0.43) | SIRT6PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL8169197 | 0.88 | DTYMK (0.47) | TSHRTDP1DTYMKALDH1A1 | |
| SCHEMBL8163021 | 0.86 | TDP1 (0.46) | SIRT6PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL8168238 | 0.80 | DTYMK (0.41) | TSHRTDP1DTYMKVCAM1ALDH1A1 | |
| SCHEMBL2722103 | 0.77 | PDGFRB (0.48) | SIRT6PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL25232489 | 0.76 | MAPT (0.52) | SIRT6PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL30457588 | 0.76 | MAPT (0.52) | SIRT6PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL28708249 | 0.75 | POLB (0.46) | TSHRTDP1POLBTPMTPKM | |
| SCHEMBL8169568 | 0.74 | KDM4E (0.50) | TSHRPOLBALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022307-A | ANGIOGENESIS INHIBITOR | AMERICAN CYANAMID COMPANY (US) | 2000-02-08 | — | — | US | disclosed |