Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | TPMT | P51580 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1013315 | 0.94 | POLB (0.50) | POLBHTTPKMTDP1CYP3A4 | |
| SCHEMBL215923 | 0.93 | TPMT (0.51) | POLBHTTPKMTPMTCYP3A4 | |
| SCHEMBL29465792 | 0.93 | TPMT (0.51) | POLBHTTPKMTPMTCYP3A4 | |
| Potassium Ion SCHEMBL2681690 | 0.91 | TPMT (0.50) | POLBHTTPKMTPMTCYP3A4 | |
| SCHEMBL2681686 | 0.91 | TPMT (0.50) | POLBHTTPKMTPMTCYP3A4 | |
| SCHEMBL3698713 | 0.90 | PKM (0.52) | POLBHTTPKMTPMTCYP3A4 | |
| SCHEMBL29734700 | 0.88 | POLB (0.50) | POLBHTTPKMTDP1CYP3A4 | |
| SCHEMBL5256629 | 0.88 | POLB (0.50) | POLBHTTPKMTDP1CYP3A4 | |
| SCHEMBL16945800 | 0.87 | PKM (0.55) | POLBHTTPKMTPMTCYP3A4 | |
| SCHEMBL28708248 | 0.86 | POLB (0.50) | POLBHTTPKMCYP3A4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114026083-A | Heterocyclic inhibitors of tyrosine kinases | 德州大学系统董事会 | 2022-02-08 | — | — | CN | disclosed |