Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 4/20 | 0.31 |
| ▸ | CA2 | P00918 | 4/20 | 0.31 |
| ▸ | CA12 | O43570 | 3/20 | 0.31 |
| ▸ | CA7 | P43166 | 3/20 | 0.31 |
| ▸ | CA9 | Q16790 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12889963 | 0.72 | CHRM3 (0.35) | TDP1CHRM3MAPTIDO1PTPN1 | |
| SCHEMBL12889966 | 0.72 | ALDH1A1 (0.38) | TDP1CHRM3MAPTLMNACHRM2 | |
| SCHEMBL10937960 | 0.72 | CHRM3 (0.45) | TDP1CHRM3MAPTLMNACHRM2 | |
| SCHEMBL817805 | 0.69 | CRHBP (0.44) | TDP1CHRM3MAPTLMNACHRM2 | |
| SCHEMBL819613 | 0.69 | CHRM3 (0.42) | TDP1CHRM3MAPTLMNACHRM2 | |
| SCHEMBL31196992 | 0.67 | TSHR (0.48) | TDP1MAPTLMNATSHRCA1 | |
| SCHEMBL17049960 | 0.65 | CHRM3 (0.40) | TDP1CHRM3MAPTPTPN1LMNA | |
| SCHEMBL817598 | 0.65 | NPC1 (0.38) | TDP1CHRM3MAPTIDO1PTPN1 | |
| SCHEMBL817072 | 0.65 | CA1 (0.39) | TDP1CHRM3MAPTLMNACHRM2 | |
| SCHEMBL818751 | 0.65 | PTPN1 (0.36) | TDP1CHRM3MAPTIDO1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236908-B2 | Components and catalysts for the polymerization of olefins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20110269927-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-03 | — | — | US | disclosed |