Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 8/20 | 0.51 |
| ▸ | BACE2 | Q9Y5Z0 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8162305 | 0.75 | BACE1 (0.49) | BACE1BACE2KMT2ALMNACYP2C9 | |
| SCHEMBL6601819 | 0.72 | BACE1 (0.49) | BACE1BACE2KMT2ALMNACYP2C9 | |
| SCHEMBL8172406 | 0.72 | BACE1 (0.49) | BACE1BACE2KMT2ALMNACYP2C9 | |
| SCHEMBL2980975 | 0.72 | BACE1 (0.61) | BACE1BACE2KMT2ALMNACYP2C9 | |
| SCHEMBL8169666 | 0.71 | BACE1 (0.47) | BACE1BACE2KMT2ALMNACYP2C9 | |
| SCHEMBL8162235 | 0.69 | BACE1 (0.49) | BACE1BACE2KMT2ALMNACYP2C9 | |
| SCHEMBL8162233 | 0.69 | BACE1 (0.49) | BACE1BACE2KMT2ALMNACYP2C9 | |
| SCHEMBL6591928 | 0.68 | BACE1 (0.61) | BACE1BACE2KMT2ALMNACYP2C9 | |
| SCHEMBL4239036 | 0.68 | BACE1 (1.00) | BACE1BACE2KMT2ALMNACYP2C9 | |
| SCHEMBL6587747 | 0.67 | BACE1 (0.43) | BACE1BACE2KMT2ALMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063934-A | Imidazolone anorectic agents: 1. 2-substituted-3,5-dihydro-5,5-diphenyl-4H-imidazol-4-ones | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-05-16 | — | — | US | disclosed |