Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 2/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | STAT1 | P42224 | 1/20 | 0.30 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6605094 | 0.76 | KDM4E (0.56) | ALDH1A1LMNAKDM4EHSD17B10NQO2 | |
| SCHEMBL6837756 | 0.76 | ALDH1A1 (0.43) | ALDH1A1LMNAKDM4EHSD17B10NQO2 | |
| SCHEMBL6839239 | 0.73 | LMNA (0.49) | ALDH1A1LMNAKDM4EHSD17B10NQO2 | |
| SCHEMBL6839318 | 0.73 | LMNA (0.49) | ALDH1A1LMNAKDM4EHSD17B10NQO2 | |
| SCHEMBL8175292 | 0.70 | ALDH1A1 (0.39) | ALDH1A1LMNAKDM4EHSD17B10NQO2 | |
| SCHEMBL25366488 | 0.68 | ALDH1A1 (0.50) | ALDH1A1LMNAKDM4EHSD17B10NQO2 | |
| SCHEMBL29361367 | 0.68 | ALDH1A1 (0.50) | ALDH1A1LMNAKDM4EHSD17B10NQO2 | |
| SCHEMBL15988845 | 0.68 | KDM4E (0.66) | ALDH1A1LMNAKDM4EHSD17B10MAPT | |
| SCHEMBL19718022 | 0.64 | KDM4E (0.45) | ALDH1A1LMNAKDM4EHSD17B10NQO2 | |
| SCHEMBL30152314 | 0.64 | KDM4E (0.45) | ALDH1A1LMNAKDM4EHSD17B10NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000058301-A1 | N-[2-(4-AMINOPHYL)ETHYL]-2,3-DIHYDRO-1,4-BENZODIOXINE-2-METHANAMINE, PRODUCTION AND THERAPEUTIC USE THEREOF | SANOFI-SYNTHELABO (FR) | 2000-10-05 | — | — | WO | disclosed |