Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL817231 | 0.87 | NPC1 (0.47) | NPC1RAB9AKMT2ALMNAOPRM1 | |
| SCHEMBL817567 | 0.84 | NPC1 (0.49) | NPC1RAB9ATP53KMT2ALMNA | |
| SCHEMBL817583 | 0.84 | NPC1 (0.49) | NPC1RAB9ATP53KMT2ALMNA | |
| SCHEMBL816947 | 0.84 | NPC1 (0.49) | NPC1RAB9ATP53KMT2ALMNA | |
| SCHEMBL17333485 | 0.78 | NPC1 (0.53) | NPC1RAB9ATP53KMT2ALMNA | |
| SCHEMBL2720763 | 0.78 | LMNA (0.59) | NPC1RAB9ATP53KMT2ALMNA | |
| SCHEMBL1690816 | 0.76 | NPC1 (0.82) | NPC1RAB9ATP53KMT2AMEN1 | |
| SCHEMBL817160 | 0.75 | HPGD (0.47) | NPC1RAB9AKMT2ALMNALTB4R2 | |
| SCHEMBL17333535 | 0.75 | NPC1 (0.53) | NPC1RAB9ATP53KMT2ALMNA | |
| SCHEMBL17333394 | 0.75 | NPC1 (0.53) | NPC1RAB9ATP53KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153545-B2 | Process for homo—or copolymerization of conjugated olefins | STYRON EUROPE GMBH (CH) | 2012-04-10 | — | — | US | disclosed |
| US-20110160041-A1 | PROCESS FOR HOMO - OR COPOLYMERIZATION OF CONJUGATED OLEFINS | STYRON EUROPE GMBH | 2011-06-30 | — | — | US | disclosed |
| US-7915194-B2 | Process for homo- or copolymerization of conjugated olefins | STYRON EUROPE GMBH (CH) | 2011-03-29 | — | — | US | disclosed |
| EP-2267046-A1 | Process for homo- or copolymerization of conjugated olefines | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-12-29 | — | — | EP | disclosed |
| US-20100248947-A1 | PROCESS FOR HOMO - OR COPOLYMERIZATION OF CONJUGATED OLEFINS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-09-30 | — | — | US | disclosed |
| US-7612009-B2 | Process for homo-or copolymerization of conjugated olefines | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2009-11-03 | — | — | US | disclosed |
| US-20060142145-A1 | Process for homo-or copolymerization of conjugated olefines | TRINSEO EUROPE GMBH (CH) | 2006-06-29 | — | — | US | disclosed |
| EP-1597292-A2 | PROCESS FOR HOMO- OR COPOLYMERIZATION OF CONJUGATED OLEFINES | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004076504-A2 | PROCESS FOR HOMO- OR COPOLYMERIZATION OF CONJUGATED OLEFINES | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2004-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160041-A1 | PROCESS FOR HOMO - OR COPOLYMERIZATION OF CONJUGATED OLEFINS | F12, ETFB, F2 | NPC1 3338/4885RAB9A 4044/4885TP53 4774/4885 |
| US-20060142145-A1 | Process for homo-or copolymerization of conjugated olefines | ETFB, F12, F2 | NPC1 3771/4885RAB9A 2984/4885TP53 4739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.