SCHEMBL817588

SCHEMBL817588

O=CC(=O)[C@H](O)[C@H](O)CO

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.41
LMNA P02545 2/20 0.38
AKR1B1 P15121 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
USP2 O75604 1/20 0.33
SLCO1B1 Q9Y6L6 1/20 0.33
OR51E2 Q9H255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL471726 1.00 PDE4A (0.41) PDE4ALMNAAKR1B1L3MBTL1TDP1
SCHEMBL1478552 1.00 PDE4A (0.41) PDE4ALMNAAKR1B1L3MBTL1TDP1
SCHEMBL29720316 1.00 PDE4A (0.41) PDE4ALMNAAKR1B1L3MBTL1TDP1
SCHEMBL29506762 0.85 PDE4A (0.48) PDE4ALMNAAKR1B1L3MBTL1TDP1
SCHEMBL15948731 0.85 PDE4A (0.48) PDE4ALMNAAKR1B1L3MBTL1TDP1
SCHEMBL5919108 0.85 PDE4A (0.48) PDE4ALMNAAKR1B1L3MBTL1TDP1
SCHEMBL29375023 0.85 PDE4A (0.48) PDE4ALMNAAKR1B1L3MBTL1TDP1
SCHEMBL818364 0.85 PDE4A (0.48) PDE4ALMNAAKR1B1L3MBTL1TDP1
SCHEMBL29502274 0.85 PDE4A (0.48) PDE4ALMNAAKR1B1L3MBTL1TDP1
SCHEMBL4258412 0.85 PDE4A (0.48) PDE4ALMNAAKR1B1L3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9133554-B2 Methods for the electrolytic production of erythritol DYNAMIC FOOD INGREDIENTS CORPORATION (US) 2015-09-15 US disclosed
EP-1982005-B1 METHODS FOR THE ELECTROLYTIC PRODUCTION OF ERYTHROSE OR ERYTHRITOL DYNAMIC FOOD INGREDIENTS CORP (US) 2013-08-07 EP disclosed
WO-2012167012-A2 METHODS FOR THE ELECTROLYTIC PRODUCTION OF ERYTHRITOL DYNAMIC FOOD INGREDIENTS CORPORATION (US) 2012-12-06 WO disclosed
US-20110272291-A1 METHODS FOR THE ELECTROLYTIC PRODUCTION OF ERYTHRITOL DFI USA, LLC 2011-11-10 US disclosed
US-7955489-B2 Methods for the electrolytic production of erythrose or erythritol DYNAMIC FOOD INGREDIENTS CORPORATION (US) 2011-06-07 US disclosed
EP-1982005-A2 METHODS FOR THE ELECTROLYTIC PRODUCTION OF ERYTHROSE OR ERYTHRITOL DYNAMIC FOOD INGREDIENTS CORP. (US) 2008-10-22 EP disclosed
WO-2007092079-A2 METHODS FOR THE ELECTROLYTIC PRODUCTION OF ERYTHROSE OR ERYTHRITOL DYNAMIC FOOD INGREDIENTS CORP. (US) 2007-08-16 WO disclosed
US-20070181437-A1 Methods for the electrolytic production of erythrose or erythritol DFI USA, LLC 2007-08-09 US disclosed
EP-0631569-B1 PRODUCTION OF XYLITOL AMYLUM NV (BE) 1997-06-18 EP disclosed
US-5563303-A Production of xylitol AMYLUM, N.V. (BE) 1996-10-08 US disclosed
EP-0631569-A1 PRODUCTION OF XYLITOL. AMYLUM NV (BE) 1995-01-04 EP disclosed
WO-1993019030-A1 PRODUCTION OF XYLITOL AMYLUM, N.V. (BE) 1993-09-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070181437-A1 Methods for the electrolytic production of erythrose or erythritol ALDOA, DERA, AGL PDE4A 4611/4885LMNA 2844/4885AKR1B1 203/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.