SCHEMBL1478552

SCHEMBL1478552

O=CC(=O)[C@H](O)[C@@H](O)CO

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.41
LMNA P02545 2/20 0.38
AKR1B1 P15121 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
USP2 O75604 1/20 0.33
SLCO1B1 Q9Y6L6 1/20 0.33
OR51E2 Q9H255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL471726 1.00 PDE4A (0.41) PDE4ALMNAAKR1B1L3MBTL1TDP1
SCHEMBL29720316 1.00 PDE4A (0.41) PDE4ALMNAAKR1B1L3MBTL1TDP1
SCHEMBL817588 1.00 PDE4A (0.41) PDE4ALMNAAKR1B1L3MBTL1TDP1
SCHEMBL29506762 0.85 PDE4A (0.48) PDE4ALMNAAKR1B1L3MBTL1TDP1
SCHEMBL15948731 0.85 PDE4A (0.48) PDE4ALMNAAKR1B1L3MBTL1TDP1
SCHEMBL5919108 0.85 PDE4A (0.48) PDE4ALMNAAKR1B1L3MBTL1TDP1
SCHEMBL29375023 0.85 PDE4A (0.48) PDE4ALMNAAKR1B1L3MBTL1TDP1
SCHEMBL818364 0.85 PDE4A (0.48) PDE4ALMNAAKR1B1L3MBTL1TDP1
SCHEMBL29502274 0.85 PDE4A (0.48) PDE4ALMNAAKR1B1L3MBTL1TDP1
SCHEMBL4258412 0.85 PDE4A (0.48) PDE4ALMNAAKR1B1L3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117317164-A Preparation method of metal alloy doped hard carbon alloy material 晖阳(贵州)新能源材料有限公司 2023-12-29 CN claimed
US-20240367975-A1 CONVERSION OF NITROGEN DIOXIDE (NO2) TO NITRIC OXIDE (NO) VERO BIOTECH INC. 2024-11-07 US disclosed
US-20240288410-A1 SELECTIVE OPTICAL AQUEOUS AND NONAQUEOUS DETECTION OF FREE SULFITES UNIV NEW YORK STATE RES FOUND (US) 2024-08-29 US disclosed
US-11884541-B2 Conversion of nitrogen dioxide (NO2) to nitric oxide (NO) VERO BIOTECH INC. (US) 2024-01-30 US disclosed
CN-117317164-A Preparation method of metal alloy doped hard carbon alloy material 晖阳(贵州)新能源材料有限公司 2023-12-29 CN disclosed
US-20230077727-A1 CONVERSION OF NITROGEN DIOXIDE (NO2) TO NITRIC OXIDE (NO) VERO BIOTECH INC. (US) 2023-03-16 US disclosed
EP-3692366-B1 SELECTIVE OPTICAL AQUEOUS AND NON-AQUEOUS DETECTION OF FREE SULFITES UNIV NEW YORK STATE RES FOUND (US) 2022-12-14 EP disclosed
US-11312626-B2 Conversion of nitrogen dioxide (NO2) to nitric oxide (NO) VERO BIOTECH INC. (US) 2022-04-26 US disclosed
US-20200180958-A1 CONVERSION OF NITROGEN DIOXIDE (NO2) TO NITRIC OXIDE (NO) Vero Biotech LLC (US) 2020-06-11 US disclosed
US-20190092639-A1 CONVERSION OF NITROGEN DIOXIDE (NO2) TO NITRIC OXIDE (NO) Vero Biotech LLC (US) 2019-03-28 US disclosed
US-20140271939-A1 CONVERSION OF NITROGEN DIOXIDE (NO2) TO NITRIC OXIDE (NO) HORIZON TECHNOLOGY FINANCE CORPORATION 2014-09-18 US disclosed
US-8741222-B2 Conversion of nitrogen dioxide (NO2) to nitric oxide (NO) GENO LLC (US) 2014-06-03 US disclosed
US-8609026-B2 Conversion of nitrogen dioxide (NO2) to nitric oxide (NO) GENO LLC (US) 2013-12-17 US disclosed
US-20120238031-A1 Conversion of Nitrogen Dioxide (NO2) to Nitric Oxide (NO) HORIZON TECHNOLOGY FINANCE CORPORATION 2012-09-20 US disclosed
US-8187544-B2 Conversion of nitrogen dioxide (NO2) to nitric oxide (NO) GENO LLC (US) 2012-05-29 US disclosed
US-20110168174-A1 Conversion of Nitrogen Dioxide (NO2) to Nitric Oxide (NO) VERO BIOTECH INC. (F/K/A VERO BIOTECH LLC) 2011-07-14 US disclosed
US-7914743-B2 Conversion of nitrogen dioxide (NO2) to nitric oxide (NO) GENO LLC (US) 2011-03-29 US disclosed
EP-2247381-A1 CONVERSION OF NITROGEN DIOXIDE (NO2) TO NITRIC OXIDE (NO) Geno LLC (US) 2010-11-10 EP disclosed
US-20090314289-A1 Conversion of Nitrogen Dioxide (NO2) to Nitric Oxide (NO) HORIZON TECHNOLOGY FINANCE CORPORATION 2009-12-24 US disclosed
WO-2009097343-A1 CONVERSION OF NITROGEN DIOXIDE (NO2) TO NITRIC OXIDE (NO) GENO LLC (US) 2009-08-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240288410-A1 SELECTIVE OPTICAL AQUEOUS AND NONAQUEOUS DETECTION OF FREE SULFITES PRDX4, PTPN12, PTPN4 PDE4A 145/4885LMNA 4644/4885AKR1B1 4114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.