Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 4/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 7/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | PRCP | P42785 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7605937 | 0.80 | HRH1 (0.45) | SIGMAR1HRH1 | |
| SCHEMBL7783140 | 0.80 | CHRM1 (0.49) | CHRM1SIGMAR1HRH1 | |
| Hydrochloric Acid SCHEMBL8191059 | 0.79 | HRH1 (0.44) | SIGMAR1HRH1 | |
| SCHEMBL8185506 | 0.76 | HRH1 (0.44) | CHRM1SIGMAR1HRH1ADRA1A | |
| SCHEMBL7782315 | 0.76 | CHRM1 (0.47) | CHRM1SIGMAR1HRH1 | |
| SCHEMBL5501785 | 0.75 | HRH1 (0.48) | CHRM1SIGMAR1HRH1HTR2AADRA1D | |
| Hydrochloric Acid SCHEMBL6969176 | 0.74 | HRH1 (0.48) | CHRM1SIGMAR1HRH1HTR2AADRA1D | |
| SCHEMBL7609166 | 0.74 | HRH1 (0.48) | CHRM1SIGMAR1HRH1 | |
| SCHEMBL20678554 | 0.74 | SIGMAR1 (0.65) | CHRM1SIGMAR1HRH1HTR2AADRA1A | |
| Hydrochloric Acid SCHEMBL8182026 | 0.73 | HRH1 (0.47) | CHRM1SIGMAR1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6066632-A | ANALGESICS; ANTIINFLAMMATORY AGENTS | NOVO NORDISK A/S (DK) | 2000-05-23 | — | — | US | disclosed |