SCHEMBL8176334

SCHEMBL8176334

C=C(C)C(=O)NC(=O)CC(N)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 10/20 0.47
GRIK2 Q13002 6/20 0.47
GRM1 Q13255 1/20 0.47
GRM2 Q14416 1/20 0.47
TGFBR1 P36897 1/20 0.42
SLC7A5 Q01650 1/20 0.41
SLC1A3 P43003 5/20 0.38
SLC1A2 P43004 5/20 0.38
SLC1A1 P43005 4/20 0.38
GRIA4 P48058 3/20 0.38
GRIK3 Q13003 3/20 0.38
GRIK5 Q16478 3/20 0.38
GRIA2 P42262 2/20 0.37
GRIA1 P42261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8176286 0.82 GRM8 (0.47) GRIK1GRIK2GRM1GRM2TGFBR1
SCHEMBL19970444 0.81 GRIK1 (0.43) GRIK1GRIK2GRM1GRM2TGFBR1
SCHEMBL19970445 0.81 GRIK1 (0.43) GRIK1GRIK2GRM1GRM2TGFBR1
SCHEMBL8353811 0.80 GRIK1 (0.50) GRIK1GRIK2GRM1GRM2SLC7A5
SCHEMBL22769505 0.80 GRIK1 (0.50) GRIK1GRIK2GRM1GRM2SLC7A5
SCHEMBL14344224 0.80 GRIK1 (0.50) GRIK1GRIK2GRM1GRM2SLC7A5
SCHEMBL9438438 0.79 GRIK1 (0.48) GRIK1GRIK2GRM1GRM2SLC7A5
SCHEMBL5277728 0.76 GRIK1 (0.51) GRIK1GRIK2GRM1GRM2SLC7A5
SCHEMBL21847970 0.74 CA12 (0.35) GRIK1GRIK2GRM1GRM2TGFBR1
SCHEMBL2954073 0.74 CA12 (0.35) GRIK1GRIK2GRM1GRM2TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115135307-A Carrier for cell delivery 株式会社ITO 2022-09-30 CN claimed
CN-115135307-B Cell delivery vehicle 株式会社ITO 2024-11-22 CN disclosed
CN-115135307-A Carrier for cell delivery 株式会社ITO 2022-09-30 CN disclosed
US-6046289-A FOR INHIBITING COAGULATION OF BLOOD PLATELETS, INHIBITING ADHESION OF ANIMAL CELLS, OR AS SUBSTRATE FOR CULTURING ANIMAL CELLS FUJIFILM CORPORATION (JP) 2000-04-04 US disclosed
EP-0488258-B1 Propenamide derivatives, polymers, copolymers and use thereof FUJI PHOTO FILM CO LTD (JP) 1996-04-17 EP disclosed
EP-0488258-A2 Propenamide derivatives, polymers, copolymers and use thereof FUJI PHOTO FILM CO., LTD. (JP) 1992-06-03 EP disclosed