SCHEMBL8176286

SCHEMBL8176286

C=C(C)C(=O)NC(=O)CCC(N)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM8 O00222 1/20 0.47
GRM6 O15303 1/20 0.47
GRIN2D O15399 1/20 0.47
GRIN3B O60391 1/20 0.47
GSR P00390 1/20 0.47
CYP1A2 P05177 1/20 0.47
GRIK1 P39086 1/20 0.47
GRM5 P41594 1/20 0.47
GRIA1 P42261 1/20 0.47
GRIA2 P42262 1/20 0.47
GRIA3 P42263 1/20 0.47
SLC1A3 P43003 1/20 0.47
SLC1A2 P43004 1/20 0.47
SLC1A1 P43005 1/20 0.47
GRIA4 P48058 1/20 0.47
GRIN1 Q05586 1/20 0.47
GRIN2A Q12879 1/20 0.47
GRIK2 Q13002 1/20 0.47
GRIK3 Q13003 1/20 0.47
GRIN2B Q13224 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8176334 0.82 GRIK1 (0.47) GRIK1GRIA1GRIA2SLC1A3SLC1A2
SCHEMBL19970446 0.82 OTC (0.44) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL19970447 0.82 OTC (0.44) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL467809 0.82 GRM8 (0.54) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL2909135 0.82 GRM8 (0.54) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL4175471 0.82 GSR (0.54) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL31562940 0.81 GSR (0.62) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL8160588 0.80 GRM8 (0.52) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL5278629 0.78 NOD1 (0.42) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL28229088 0.77 GSR (0.58) GRM8GRM6GRIN2DGRIN3BGSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111542754-B Microcapsules for detecting and/or quantifying analytes in a sample 布林克公司 2025-03-11 CN claimed
CN-118510909-A Microsphere comprising a first material and a second material 布林克公司 2024-08-16 CN claimed
CN-111542754-B Microcapsules for detecting and/or quantifying analytes in a sample 布林克公司 2025-03-11 CN disclosed
CN-118510909-A Microsphere comprising a first material and a second material 布林克公司 2024-08-16 CN disclosed
US-6046289-A FOR INHIBITING COAGULATION OF BLOOD PLATELETS, INHIBITING ADHESION OF ANIMAL CELLS, OR AS SUBSTRATE FOR CULTURING ANIMAL CELLS FUJIFILM CORPORATION (JP) 2000-04-04 US disclosed
EP-0488258-B1 Propenamide derivatives, polymers, copolymers and use thereof FUJI PHOTO FILM CO LTD (JP) 1996-04-17 EP disclosed
EP-0488258-A2 Propenamide derivatives, polymers, copolymers and use thereof FUJI PHOTO FILM CO., LTD. (JP) 1992-06-03 EP disclosed