Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8191077 | 0.94 | EDNRB (0.88) | EDNRBEDNRA | |
| SCHEMBL8185019 | 0.94 | EDNRB (1.00) | EDNRBEDNRA | |
| SCHEMBL8180058 | 0.94 | EDNRB (1.00) | EDNRBEDNRA | |
| SCHEMBL8189503 | 0.94 | EDNRB (1.00) | EDNRBEDNRA | |
| SCHEMBL8189498 | 0.94 | EDNRB (1.00) | EDNRBEDNRA | |
| SCHEMBL8185879 | 0.92 | EDNRB (0.96) | EDNRBEDNRA | |
| A-192621 SCHEMBL1030269 | 0.88 | EDNRB (1.00) | EDNRBEDNRA | |
| A-192621 SCHEMBL22404939 | 0.88 | EDNRB (1.00) | EDNRBEDNRA | |
| SCHEMBL8176298 | 0.88 | EDNRB (0.94) | EDNRBEDNRA | |
| A-192621 SCHEMBL29551251 | 0.88 | EDNRB (1.00) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124341-A | A DRUG FOR TREATING HYPERTENSION, CONGESTIVE HEART FAILURE, RESTENOSIS FOLLOWING ARTERIAL INJURY, CEREBRAL OR MYOCARDIAL ISCHEMIA OR ATHEROSCLEROSIS; VASODILUTOR | ABBOTT LABORATORIES (US) | 2000-09-26 | — | — | US | disclosed |