Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.78 |
| ▸ | LMNA | P02545 | 4/20 | 0.78 |
| ▸ | ATM | Q13315 | 3/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.78 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.78 |
| ▸ | SHBG | P04278 | 2/20 | 0.78 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.78 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.78 |
| ▸ | FYN | P06241 | 1/20 | 0.78 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.78 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.78 |
| ▸ | HTR2B | P41595 | 1/20 | 0.78 |
| ▸ | HTT | P42858 | 1/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.63 |
| ▸ | PGR | P06401 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14360870 | 1.00 | ESR1 (0.78) | ESR1LMNAATMSMN1; SMN2NR3C1 | |
| SCHEMBL10360627 | 0.91 | ESR1 (0.73) | ESR1LMNAATMSMN1; SMN2NR3C1 | |
| SCHEMBL8208515 | 0.89 | ESR1 (0.71) | ESR1LMNAATMSMN1; SMN2NR3C1 | |
| SCHEMBL8208518 | 0.88 | ESR1 (0.72) | ESR1LMNAATMSMN1; SMN2NR3C1 | |
| SCHEMBL11217743 | 0.88 | ESR1 (0.69) | ESR1LMNAATMSMN1; SMN2NR3C1 | |
| Estradiol Benzoate SCHEMBL12180364 | 0.88 | ESR1 (1.00) | ESR1LMNAATMSMN1; SMN2NR3C1 | |
| Estradiol Benzoate SCHEMBL301616 | 0.88 | ESR1 (1.00) | ESR1LMNAATMSMN1; SMN2NR3C1 | |
| Estradiol Benzoate SCHEMBL22049057 | 0.88 | ESR1 (1.00) | ESR1LMNAATMSMN1; SMN2NR3C1 | |
| Estradiol Benzoate SCHEMBL18467889 | 0.88 | ESR1 (1.00) | ESR1LMNAATMSMN1; SMN2NR3C1 | |
| Estradiol Benzoate SCHEMBL174896 | 0.88 | ESR1 (1.00) | ESR1LMNAATMSMN1; SMN2NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111433577-B | Temperature detection label and article management device using same | 株式会社日立制作所 | 2021-09-21 | — | — | CN | disclosed |
| CN-110603431-B | Temperature detection material, temperature detection ink using same, temperature indicator, and article management system | 株式会社日立产机系统 | 2021-06-15 | — | — | CN | disclosed |
| EP-2484383-B1 | METHOD FOR IMPROVING THE AQUEOUS SOLUBILITY OF POORLY-SOLUBLE SUBSTANCES | SANGI KK (JP) | 2021-04-28 | — | — | EP | disclosed |
| EP-3054940-B1 | COMPOSITIONS AND METHODS FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS | MOCHIDA PHARM CO LTD (JP) | 2020-09-23 | — | — | EP | disclosed |
| CN-110603431-A | Temperature detection material, temperature detection ink using same, temperature indicator, and article management system | 株式会社日立产机系统 | 2019-12-20 | — | — | CN | disclosed |
| EP-3054940-A1 | COMPOSITIONS AND METHODS FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS | Mochida Pharmaceutical Co., Ltd. (JP) | 2016-08-17 | — | — | EP | disclosed |
| US-20160213639-A1 | COMPOSITIONS AND METHODS FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2016-07-28 | — | — | US | disclosed |
| US-9248103-B2 | Method for improving water solubility of slightly soluble substance | KABUSHIKI KAISHA SANGI (JP) | 2016-02-02 | — | — | US | disclosed |
| US-9023398-B2 | Method for improving the aqueous solubility of poorly-soluble substances | KABUSHIKI KAISHA SANGI (JP) | 2015-05-05 | — | — | US | disclosed |
| WO-2015053379-A1 | COMPOSITIONS AND METHODS FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2015-04-16 | — | — | WO | disclosed |
| EP-0873751-A2 | Pharmaceutical product for application to uterus mucosa | TAKEDA CHEMICAL INDUSTRIES, Ltd. (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5578589-A | Method for suppressing an immunoresponse with an estradiol derivative-chlorambucil conjugate | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| US-5576309-A | HEMATOPOIETIC OR SOLID TUMOR TREATMENT | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| US-5354745-A | Antitumor agents | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-10-11 | — | — | US | disclosed |
| EP-0424954-B1 | Pharmaceutical composition for treatment of osteoporosis | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 1994-04-27 | — | — | EP | disclosed |
| US-5116828-A | Estrogen and thyroid hormone | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0253901-B1 | SUSTAINED-RELEASE PREPARATION | TEIJIN LIMITED (JP) | 1991-12-27 | — | — | EP | disclosed |
| EP-0424954-A1 | Pharmaceutical composition for treatment of osteoporosis | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |
| US-4990340-A | Percutaneous administration without skin irritability | TEIJIN LIMITED (JP) | 1991-02-05 | — | — | US | disclosed |
| EP-0253901-A1 | SUSTAINED-RELEASE PREPARATION | TEIJIN LIMITED (JP) | 1988-01-27 | — | — | EP | disclosed |