Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.72 |
| ▸ | LMNA | P02545 | 5/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.72 |
| ▸ | ATM | Q13315 | 2/20 | 0.72 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.72 |
| ▸ | SHBG | P04278 | 2/20 | 0.72 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.72 |
| ▸ | FYN | P06241 | 1/20 | 0.72 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.72 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.72 |
| ▸ | HTR2B | P41595 | 1/20 | 0.72 |
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | PGR | P06401 | 2/20 | 0.59 |
| ▸ | AR | P10275 | 2/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL347436 | 0.93 | ESR1 (0.67) | ESR1LMNASMN1; SMN2KMT2AADORA3 | |
| SCHEMBL5711620 | 0.92 | LMNA (0.68) | ESR1LMNASMN1; SMN2KMT2AADORA3 | |
| SCHEMBL21540422 | 0.90 | SMN1; SMN2 (0.72) | ESR1LMNASMN1; SMN2KMT2AADORA3 | |
| SCHEMBL10960504 | 0.90 | SMN1; SMN2 (0.72) | ESR1LMNASMN1; SMN2KMT2AADORA3 | |
| SCHEMBL8208515 | 0.89 | ESR1 (0.71) | ESR1LMNASMN1; SMN2KMT2AADORA3 | |
| SCHEMBL8177995 | 0.88 | ESR1 (0.78) | ESR1LMNASMN1; SMN2KMT2AADORA3 | |
| SCHEMBL14360870 | 0.88 | ESR1 (0.78) | ESR1LMNASMN1; SMN2KMT2AADORA3 | |
| SCHEMBL8155723 | 0.86 | MAPT (0.81) | ESR1LMNASMN1; SMN2KMT2AADORA3 | |
| SCHEMBL7528824 | 0.85 | MAPT (0.76) | ESR1LMNASMN1; SMN2KMT2AADORA3 | |
| SCHEMBL7528821 | 0.85 | MAPT (0.76) | ESR1LMNASMN1; SMN2KMT2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1016417-A1 | PRESSURE-SENSITIVE ADHESIVES FOR PERCUTANEOUS PLASTERS AND PERCUTANEOUS PLASTERS | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 2000-07-05 | — | — | EP | disclosed |