Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | NAT1 | P18440 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15849847 | 0.84 | PTGS2 (0.47) | PTGS2ALDH1A1RAB9AMAPTHPGD | |
| SCHEMBL8597480 | 0.84 | PTGS2 (0.47) | PTGS2ALDH1A1RAB9AMAPTHPGD | |
| SCHEMBL250146 | 0.84 | PTGS2 (0.56) | PTGS2PTGS1KDM4EALDH1A1RAB9A | |
| SCHEMBL232659 | 0.84 | CASP1 (0.47) | PTGS2ALDH1A1HPGD | |
| SCHEMBL29743050 | 0.84 | CASP1 (0.47) | PTGS2ALDH1A1HPGD | |
| SCHEMBL5320291 | 0.82 | TSHR (0.52) | PTGS2PTGS1ALDH1A1 | |
| SCHEMBL890902 | 0.82 | ABL1 (0.48) | RAB9AMAPTF10MAOB | |
| SCHEMBL4202592 | 0.82 | PTGS2 (0.55) | PTGS2PTGS1KDM4EALDH1A1RAB9A | |
| SCHEMBL28934633 | 0.82 | CASP1 (0.46) | PTGS2ALDH1A1HPGD | |
| SCHEMBL29353151 | 0.82 | PTGS2 (0.48) | PTGS2ALDH1A1RAB9ACYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013836-A | PARTICULARLY ACTIVE AGAINST MOTHS AND BEETLES AND THEIR INSECT GROWTH REGULATING ACTIVITY WITHOUT ADVERSE IMPACT ON BENEFICIAL INSECTS; CROPS; FORESTRY | ROHM AND HAAS COMPANY (US) | 2000-01-11 | — | — | US | disclosed |
| US-5470984-A | Insecticides, molluscicides | SHELL RESEARCH LIMITED (GB) | 1995-11-28 | — | — | US | disclosed |
| US-5354762-A | Insecticides | ROHM AND HAAS COMPANY (US) | 1994-10-11 | — | — | US | disclosed |
| US-5342958-A | Insecticides | SOLVAY DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1994-08-30 | — | — | US | disclosed |
| EP-0338685-B1 | 1-Dimethylcarbamoyl-3-substituted-5-substituted-1H-1,2,4-triazoles | SHELL INT RESEARCH (NL) | 1994-06-29 | — | — | EP | disclosed |
| US-5319092-A | Insecticides, miticides, aphidicides, molluscicides and plant growth regulators | SHELL RESEARCH LIMITED (GB) | 1994-06-07 | — | — | US | disclosed |
| EP-0311284-B1 | Insecticidal hydrogenated neem extracts | ROHM & HAAS (US) | 1994-04-06 | — | — | EP | disclosed |
| US-5245071-A | Insecticides | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1993-09-14 | — | — | US | disclosed |
| EP-0347216-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYLHYDRAZINES AND N'-SUBSTITUTED -N-ACYL-N'-ALKYLCARBONYL HYDRAZINES | ROHM AND HAAS COMPANY (US) | 1993-09-01 | — | — | EP | disclosed |
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| US-3960947-A | FORMAMIDINE COMPOUNDS, PESTICIDES | CIBA-GEIGY CORPORATION (US) | 1976-06-01 | — | — | US | disclosed |
| US-3956306-A | PESTICIDES | CIBA-GEIGY CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |
| US-3948940-A | Pesticidal phthalimido phosphorous ester compounds | CIBA-GEIGY CORPORATION (US) | 1976-04-06 | — | — | US | disclosed |
| US-3941829-A | PESTICIDE | CIBA-GEIGY CORPORATION (US) | 1976-03-02 | — | — | US | disclosed |
| US-3940412-A | 2,4,5-Trichloro- and 2,4,5-tribromoimidazole derivatives and pesticidal compositions containing them | CIBA-GEIGY AG (CH) | 1976-02-24 | — | — | US | disclosed |
| US-3935224-A | 4H-Pyrido[3,2a]-1,3,2-dioxophosphorane derivatives | CIBA-GEIGY CORPORATION (US) | 1976-01-27 | — | — | US | disclosed |
| US-3933908-A | INSECTICIDE | U.S. PHILIPS CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |
| US-3933945-A | O-ethyl-S-(n)propyl-S-diallylcarbmoylmethyldithiophosphate | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |
| US-3932629-A | Triazolyl phosphorus esters as pesticides | CIBA-GEIGY CORPORATION (US) | 1976-01-13 | — | — | US | disclosed |
| US-3932630-A | Triazolyl phosphorus esters as pesticides | CIBA-GEIGY CORPORATION (US) | 1976-01-13 | — | — | US | disclosed |