Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 6/20 | 0.70 |
| ▸ | ICMT | O60725 | 10/20 | 0.66 |
| ▸ | PPARD | Q03181 | 4/20 | 0.66 |
| ▸ | PPARG | P37231 | 3/20 | 0.66 |
| ▸ | PPARA | Q07869 | 3/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13930965 | 0.91 | PPARD (0.77) | PLA2G2AICMTPPARDPPARGPPARA | |
| SCHEMBL13930968 | 0.89 | PPARD (0.68) | PLA2G2AICMTPPARDPPARGPPARA | |
| SCHEMBL8178996 | 0.89 | ICMT (0.61) | PLA2G2AICMTPPARDPPARGPPARA | |
| SCHEMBL8174606 | 0.88 | PPARD (0.72) | PLA2G2AICMTPPARDPPARGPPARA | |
| SCHEMBL8171659 | 0.87 | PPARD (0.82) | PLA2G2AICMTPPARDPPARGPPARA | |
| SCHEMBL13931174 | 0.86 | PPARD (0.64) | PLA2G2AICMTPPARDPPARGPPARA | |
| SCHEMBL8175701 | 0.85 | LMNA (0.61) | PLA2G2AICMTPPARDPPARGPPARA | |
| SCHEMBL8174602 | 0.84 | PPARD (0.70) | PLA2G2AICMTPPARDPPARGPPARA | |
| SCHEMBL8175413 | 0.84 | PPARD (0.62) | PLA2G2AICMTPPARDPPARGPPARA | |
| SCHEMBL8167580 | 0.84 | LMNA (0.61) | PLA2G2AICMTPPARDPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008100867-A2 | NOVEL INHIBITORS HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2008-08-21 | — | — | WO | disclosed |