Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.53 |
| ▸ | PPARG | P37231 | 3/20 | 0.51 |
| ▸ | PPARD | Q03181 | 3/20 | 0.51 |
| ▸ | PPARA | Q07869 | 3/20 | 0.51 |
| ▸ | ICMT | O60725 | 1/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.48 |
| ▸ | CDC25A | P30304 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8178907 | 0.89 | ALDH1A1 (0.56) | ALDH1A1LMNAMCL1PPARGPPARD | |
| SCHEMBL8178901 | 0.88 | ALDH1A1 (0.60) | ALDH1A1LMNAMCL1PPARGPPARD | |
| SCHEMBL13931026 | 0.87 | ALDH1A1 (0.65) | ALDH1A1LMNAMCL1PPARGPPARD | |
| SCHEMBL13931411 | 0.87 | ALDH1A1 (0.56) | ALDH1A1LMNAMCL1PPARGPPARD | |
| SCHEMBL8180736 | 0.85 | ALDH1A1 (0.55) | ALDH1A1LMNAMCL1PPARGPPARD | |
| SCHEMBL8182990 | 0.85 | PPARG (0.62) | ALDH1A1LMNAMCL1PPARGPPARD | |
| SCHEMBL8180730 | 0.85 | ALDH1A1 (0.60) | ALDH1A1LMNAMCL1PPARGPPARD | |
| SCHEMBL8186676 | 0.85 | ALDH1A1 (0.54) | ALDH1A1LMNAMCL1PPARGPPARD | |
| SCHEMBL8179889 | 0.85 | LMNA (0.60) | ALDH1A1LMNAMCL1PPARGPPARD | |
| SCHEMBL8181052 | 0.84 | ALDH1A1 (0.56) | ALDH1A1LMNAMCL1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008100867-A2 | NOVEL INHIBITORS HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2008-08-21 | — | — | WO | disclosed |