Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8175913 | 0.93 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL8181501 | 0.88 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL8174556 | 0.80 | CRHR1 (0.66) | CRHR1 | |
| SCHEMBL7838650 | 0.76 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL8181519 | 0.75 | CRHR1 (0.62) | CRHR1 | |
| SCHEMBL8166738 | 0.73 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL8173716 | 0.68 | CRHR1 (0.66) | CRHR1 | |
| SCHEMBL7620621 | 0.66 | CRHR1 (0.90) | CRHR1 | |
| SCHEMBL6295034 | 0.64 | CRHR1 (0.62) | CRHR1 | |
| SCHEMBL5495058 | 0.64 | CRHR1 (0.61) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107294-A | NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | DUPONT PHARMACEUTICALS (US) | 2000-08-22 | — | — | US | claimed |
| US-6107294-A | NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | DUPONT PHARMACEUTICALS (US) | 2000-08-22 | — | — | US | disclosed |