Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8174266 | 0.90 | CRHR1 (0.62) | CRHR1 | |
| SCHEMBL5495331 | 0.76 | CRHR1 (0.50) | CRHR1 | |
| SCHEMBL8178609 | 0.75 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL8174556 | 0.73 | CRHR1 (0.66) | CRHR1 | |
| SCHEMBL7838650 | 0.71 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL8175913 | 0.71 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL8178987 | 0.70 | CRHR1 (0.56) | CRHR1 | |
| SCHEMBL7474752 | 0.68 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL5491177 | 0.66 | CRHR1 (0.58) | CRHR1 | |
| SCHEMBL7628570 | 0.66 | CRHR1 (1.00) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107294-A | NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | DUPONT PHARMACEUTICALS (US) | 2000-08-22 | — | — | US | claimed |
| US-6107294-A | NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | DUPONT PHARMACEUTICALS (US) | 2000-08-22 | — | — | US | disclosed |