Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | XPO1 | O14980 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7679948 | 0.88 | HDAC6 (0.42) | MAPTTHRBALDH1A1SMN1; SMN2CNR2 | |
| SCHEMBL8171121 | 0.87 | ALDH1A1 (0.48) | MAPTTHRBALDH1A1SMN1; SMN2CNR2 | |
| SCHEMBL8176732 | 0.87 | MAPT (0.46) | MAPTTHRBALDH1A1SMN1; SMN2CNR2 | |
| SCHEMBL8172706 | 0.86 | MAPT (0.44) | MAPTTHRBALDH1A1SMN1; SMN2CNR2 | |
| SCHEMBL8172685 | 0.85 | MAPT (0.45) | MAPTTHRBALDH1A1SMN1; SMN2CNR2 | |
| SCHEMBL8177180 | 0.84 | MAPT (0.44) | MAPTTHRBALDH1A1SMN1; SMN2CNR2 | |
| SCHEMBL8171546 | 0.84 | MAPT (0.43) | MAPTTHRBALDH1A1SMN1; SMN2CNR2 | |
| SCHEMBL8176656 | 0.83 | CASP1 (0.44) | MAPTTHRBALDH1A1SMN1; SMN2CNR2 | |
| SCHEMBL8177175 | 0.83 | MAPT (0.43) | MAPTTHRBALDH1A1SMN1; SMN2CNR2 | |
| SCHEMBL8179077 | 0.82 | MAPT (0.42) | MAPTTHRBALDH1A1SMN1; SMN2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136834-A | TETRAZOLE PEPTIDES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0900791-A1 | TETRAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-10 | — | — | EP | disclosed |