Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8178705 | 1.00 | ALDH1A1 (0.45) | ALDH1A1HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8181774 | 0.91 | PDE4A (0.51) | ALDH1A1MEN1KMT2APTPN11PDE4A | |
| SCHEMBL8181773 | 0.91 | PDE4A (0.51) | ALDH1A1MEN1KMT2APTPN11PDE4A | |
| SCHEMBL8178709 | 0.83 | CREBBP (0.60) | ALDH1A1HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3184382 | 0.81 | PTPN11 (0.55) | ALDH1A1PTPN11 | |
| SCHEMBL7691383 | 0.81 | LMNA (0.51) | ALDH1A1HPGDPTPN11TP53TSHR | |
| SCHEMBL7691386 | 0.81 | LMNA (0.51) | ALDH1A1HPGDPTPN11TP53TSHR | |
| SCHEMBL8170140 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HPGDSMN1; SMN2PTPN11TP53 | |
| SCHEMBL8636324 | 0.81 | MAPT (0.53) | ALDH1A1HPGDPTPN11TP53TSHR | |
| SCHEMBL8636321 | 0.81 | MAPT (0.53) | ALDH1A1HPGDPTPN11TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143208-A | Optical element and compounds used in its manufacture | ROLIC AG (CH) | 2000-11-07 | — | — | US | disclosed |
| US-5335303-A | Quasi-phased matched optical waveguide frequency conversion element having a ferroelectric liquid crystalline material exhibiting a periodic structure | HOFFMANN-LA ROCHE INC. (US) | 1994-08-02 | — | — | US | disclosed |