Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.82 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 4/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3073739 | 0.91 | CA2 (1.00) | CA2MAOBPPARGFFAR1KMT2A | |
| SCHEMBL8172791 | 0.81 | CA2 (0.71) | CA2MAOBPPARGFFAR1KMT2A | |
| SCHEMBL12961220 | 0.81 | CA2 (0.71) | CA2MAOBPPARGKMT2AMAPT | |
| SCHEMBL13598470 | 0.78 | CA2 (0.51) | CA2PPARGFFAR1KMT2A | |
| SCHEMBL8173454 | 0.77 | CA2 (0.61) | CA2PPARGFFAR1KMT2AMAPT | |
| SCHEMBL8192161 | 0.76 | CA2 (0.73) | CA2MAOBPPARGKMT2AMAPT | |
| SCHEMBL8173637 | 0.75 | CA2 (0.62) | CA2MAOBPPARGKMT2AMAPT | |
| SCHEMBL13846966 | 0.75 | CA2 (0.62) | CA2PPARGFFAR1KMT2AMAPT | |
| SCHEMBL8172141 | 0.75 | CA2 (0.62) | CA2MAOBPPARGKMT2AMAPT | |
| SCHEMBL8172144 | 0.75 | CA2 (0.62) | CA2MAOBPPARGKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018748-A1 | RHODANINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF METABOLIC BONE DISORDERS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |