Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.73 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | FASN | P49327 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8165382 | 0.92 | CA2 (0.68) | CA2MAOBKMT2AFASNPPARG | |
| SCHEMBL3073739 | 0.85 | CA2 (1.00) | CA2MAOBKMT2APPARGMAPT | |
| SCHEMBL8177729 | 0.80 | CA2 (0.57) | CA2MAOBKMT2AMAPTGLA | |
| SCHEMBL3075482 | 0.80 | CA2 (0.56) | CA2MAOBKMT2AMAPTKDM4E | |
| SCHEMBL8179232 | 0.76 | CA2 (0.82) | CA2MAOBKMT2APPARGMAPT | |
| SCHEMBL8208034 | 0.75 | PPARG (0.51) | CA2MAOBKMT2APPARGMAPT | |
| SCHEMBL8173510 | 0.75 | CA2 (0.62) | CA2MAOBKMT2APPARGMAPT | |
| SCHEMBL19217794 | 0.74 | FFAR1 (0.56) | MAOBPPARG | |
| SCHEMBL4137563 | 0.72 | KMT2A (0.62) | KMT2AMAPTLMNAGLAALDH1A1 | |
| SCHEMBL4137564 | 0.72 | KMT2A (0.62) | KMT2AMAPTLMNAGLAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018748-A1 | RHODANINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF METABOLIC BONE DISORDERS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |