SCHEMBL8179403

SCHEMBL8179403

COC(CNC(=O)CCC(N)=O)OC

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
MAPK1 P28482 2/20 0.36
TDP1 Q9NUW8 1/20 0.35
ALDH1A1 P00352 3/20 0.34
RECQL P46063 1/20 0.34
HPGD P15428 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TSHR P16473 1/20 0.32
TLR2 O60603 1/20 0.31
MTNR1A P48039 1/20 0.31
MTNR1B P49286 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29010635 0.91 TSHR (0.43) MEN1KMT2AMAPK1TDP1ALDH1A1
SCHEMBL30366355 0.90 MEN1 (0.41) MEN1KMT2AMAPK1TDP1ALDH1A1
SCHEMBL19743724 0.82 TLR2 (0.44) MEN1KMT2AMAPK1ALDH1A1RECQL
SCHEMBL2296514 0.82 PHF8 (0.42) MEN1KMT2AALDH1A1RECQLTSHR
SCHEMBL2354778 0.81 EPHX1 (0.40) MEN1KMT2AMAPK1ALDH1A1SMN1; SMN2
SCHEMBL5666064 0.78 MEN1 (0.37) MEN1KMT2AMAPK1TDP1ALDH1A1
SCHEMBL14497219 0.78 MEN1 (0.35) MEN1KMT2AMAPK1TDP1ALDH1A1
SCHEMBL743998 0.78 CYP2D6 (0.48) ALDH1A1RECQLHPGDSMN1; SMN2
SCHEMBL3784058 0.77 KMT2A (0.41) MEN1KMT2AMAPK1TDP1ALDH1A1
SCHEMBL6924528 0.77 RECQL (0.42) MEN1KMT2AMAPK1RECQLHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115990441-A Preparation system and preparation method of polyvinyl alcohol embolism microsphere with uniform particle size 赛克赛斯生物科技股份有限公司 2023-04-21 CN claimed
CN-115990441-A Preparation system and preparation method of polyvinyl alcohol embolism microsphere with uniform particle size 赛克赛斯生物科技股份有限公司 2023-04-21 CN disclosed
US-6011077-A DERIVATIVE OF A POLYVINYL ALCOHOL COMPRISING UNITS CONTAINING CROSSLINKABLE OLEFINICALLY UNSATURATED GROUPS, AND UNITS CONTAINING A BONDED PHOTOINITATOR NOVARTIS AG (CH) 2000-01-04 US disclosed
EP-0807269-B1 CROSSLINKABLE POLYMERS CONTAINING PHOTOINITIATORS NOVARTIS AG (CH) 1999-10-20 EP disclosed
EP-0807269-A1 CROSSLINKED POLYMERS CONTAINING PHOTOINITIATORS Novartis AG (CH) 1997-11-19 EP disclosed
WO-1996024077-A1 CROSSLINKED POLYMERS CONTAINING PHOTOINITIATORS NOVARTIS AG (CH) 1996-08-08 WO disclosed