SCHEMBL3784058

SCHEMBL3784058

COC(CNC(N)=O)OC

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.41
MEN1 O00255 3/20 0.41
TDP1 Q9NUW8 2/20 0.39
BCAT2 O15382 1/20 0.38
ALDH1A1 P00352 5/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
LMNA P02545 1/20 0.35
HPGD P15428 1/20 0.35
KDM4E B2RXH2 3/20 0.34
MAPT P10636 2/20 0.34
GLA P06280 1/20 0.34
GAA P10253 1/20 0.34
MAPK1 P28482 1/20 0.33
POLB P06746 1/20 0.33
RECQL P46063 1/20 0.33
GFPT1 Q06210 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19384149 0.82 KMT2A (0.39) KMT2AMEN1TDP1ALDH1A1SMN1; SMN2
SCHEMBL1872795 0.78 MTNR1A (0.43) KMT2AMEN1TDP1ALDH1A1SMN1; SMN2
SCHEMBL6399291 0.78 CYP2D6 (0.54) KMT2AMEN1TDP1ALDH1A1SMN1; SMN2
SCHEMBL28118524 0.77 MTNR1A (0.32) TDP1
SCHEMBL11779858 0.77 EPHX1 (0.45) KMT2AMEN1TDP1BCAT2ALDH1A1
SCHEMBL28738943 0.77
SCHEMBL8179403 0.77 MEN1 (0.37) KMT2AMEN1TDP1ALDH1A1SMN1; SMN2
SCHEMBL7450284 0.76 ALDH1A1 (0.38) KMT2AMEN1TDP1ALDH1A1SMN1; SMN2
SCHEMBL30366355 0.76 MEN1 (0.41) KMT2AMEN1TDP1ALDH1A1SMN1; SMN2
SCHEMBL15739721 0.76 MEN1 (0.34) KMT2AMEN1TDP1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106414411-A Formulation and process for finishing textiles 巴斯夫欧洲公司 2017-02-15 CN claimed
US-6730470-B2 SENSITIVITY, HIGH DEVELOPING SPEED AND LITTLE PERFORMANCE FLUCTUATION DUE TO VARIATION OF HEAT DEVELOPMENT TEMPERATURE FUJI PHOTO FILM CO., LTD. (JP) 2004-05-04 US claimed
US-20020086251-A1 Photothermographic material FUJIFILM CORPORATION (JP) 2002-07-04 US claimed
CN-120136870-A GLP-1 receptor targeting compounds and uses thereof 信达生物科技有限公司 2025-06-13 CN disclosed
WO-2025119206-A1 GLP-1 RECEPTOR TARGETING COMPOUNDS AND USES THEREOF FORTVITA BIOLOGICS INC. (KY) 2025-06-12 WO disclosed
EP-4351560-A1 ANTICANCER COMPOUNDS The Regents of the University of California (US) 2024-04-17 EP disclosed
WO-2022261204-A1 ANTICANCER COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-12-15 WO disclosed
CN-110872466-B Water-based coating composition, conductive elastomer roller, method for producing same, process cartridge using same, and image forming apparatus 纳思达股份有限公司 2021-12-07 CN disclosed
CN-110872466-A Water-based coating composition, conductive elastomer roller, method for producing same, process cartridge using same, and image forming apparatus 纳思达股份有限公司 2020-03-10 CN disclosed
CN-103097340-B Therapeutically active compositions and methods of use thereof 安吉奥斯医药品有限公司 2018-03-16 CN disclosed
CN-106414411-A Formulation and process for finishing textiles 巴斯夫欧洲公司 2017-02-15 CN disclosed
CN-102803250-B 1, 3-disubstituted imidazolidin-2-one derivatives as inhibitors of CYP17 NOVARTIS AG 2014-04-16 CN disclosed
CN-102803250-A 1, 3-disubstituted imidazolidin-2-one derivatives as inhibitors of CYP17 NOVARTIS AG 2012-11-28 CN disclosed
EP-2398809-A1 NOVEL SPIRO COMPOUNDS USEFUL AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE Merck Canada Inc. (CA) 2011-12-28 EP disclosed
WO-2010094120-A1 NOVEL SPIRO COMPOUNDS USEFUL AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE MERCK FROSST CANADA LTD. (CA) 2010-08-26 WO disclosed
US-6730470-B2 SENSITIVITY, HIGH DEVELOPING SPEED AND LITTLE PERFORMANCE FLUCTUATION DUE TO VARIATION OF HEAT DEVELOPMENT TEMPERATURE FUJI PHOTO FILM CO., LTD. (JP) 2004-05-04 US disclosed
CN-1103760-C 1, 3-dihydro-2H-imidazol-2-one derivatives having PDEIV and cytokine inhibitory activity JANSSEN PHARMACEUTICA NV (BE) 2003-03-26 CN disclosed
US-20020086251-A1 Photothermographic material FUJIFILM CORPORATION (JP) 2002-07-04 US disclosed
CN-1181073-A 1, 3 -dihydro -2H -imidazol -2 -one derivatives having PDEIV and cytokinin inhibiting activity JANSSEN PHARMACEUTICA NV (BE) 1998-05-06 CN disclosed
EP-0034456-B1 3-(SUBSTITUTED 3- OR 5-ISOXAZOLYL)-1-4-, OR 5-SUBSTITUTED-2-IMIDAZOLIDINONES, METHODS FOR THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND THEIR USE AS HERBICIDES PPG INDUSTRIES, INC. (US) 1984-08-15 EP disclosed