Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 5/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | KDM5C | P41229 | 3/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30366355 | 0.92 | MEN1 (0.41) | TSHRMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL8179403 | 0.82 | MEN1 (0.37) | TSHRMEN1KMT2AALDH1A1RECQL | |
| SCHEMBL19743724 | 0.80 | TLR2 (0.44) | KDM4EMEN1KMT2AALDH1A1RECQL | |
| SCHEMBL5666064 | 0.80 | MEN1 (0.37) | KDM4ETSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL14497219 | 0.79 | MEN1 (0.35) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| SCHEMBL6924528 | 0.78 | RECQL (0.42) | TSHRMEN1KMT2ARECQL | |
| SCHEMBL29010635 | 0.77 | TSHR (0.43) | TSHRMEN1KMT2AALDH1A1RECQL | |
| SCHEMBL18373774 | 0.77 | FAAH (0.55) | MEN1KMT2ARECQL | |
| SCHEMBL5572365 | 0.77 | TSHR (0.56) | TSHRMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7094098 | 0.77 | CYP2D6 (0.56) | PHF8KDM2AKDM4EKDM5CEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110189253-A1 | BIOMATERIAL COMPOSITION AND METHOD | WARSAW ORTHOPEDIC, INC. (US) | 2011-08-04 | — | — | US | disclosed |
| EP-1773253-B1 | SPINAL DISC NUCLEUS PULPOSUS IMPLANT | BIOCURE INC (US) | 2010-11-24 | — | — | EP | disclosed |
| US-7666225-B2 | Spinal disc nucleus pulposus implant | BIOCURE, INC. | 2010-02-23 | — | — | US | disclosed |
| EP-1773253-A4 | SPINAL DISC NUCLEUS PULPOSUS IMPLANT | BIOCURE INC (US) | 2009-02-18 | — | — | EP | disclosed |
| EP-1773358-A2 | BIOMATERIAL | BioCure, Inc. (US) | 2007-04-18 | — | — | EP | disclosed |
| EP-1773253-A2 | SPINAL DISC NUCLEUS PULPOSUS IMPLANT | BioCure, Inc. (US) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006004941-A2 | BIOMATERIAL | BIOCURE, INC. (US) | 2006-01-12 | — | — | WO | disclosed |
| WO-2006004940-A2 | SPINAL DISC NUCLEUS PULPOSUS IMPLANT | BIOCURE, INC. (US) | 2006-01-12 | — | — | WO | disclosed |
| US-20050288789-A1 | Spinal disc nucleus pulposus implant | BIOCURE, INC. | 2005-12-29 | — | — | US | disclosed |
| US-20050287218-A1 | Biomaterial | BIOCURE, INC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110189253-A1 | BIOMATERIAL COMPOSITION AND METHOD | ILK, KIT, CAD | PHF8 2754/4885KDM2A 569/4885KDM4E 1214/4885 |
| US-20050287218-A1 | Biomaterial | BMP2, ADM2, BMP1 | PHF8 4005/4885KDM2A 2271/4885KDM4E 3586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.