Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 6/20 | 0.49 |
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8175776 | 0.87 | CES2 (0.46) | TMPRSS4CES2CES1MEN1KMT2A | |
| SCHEMBL8182159 | 0.82 | TMPRSS4 (0.49) | TMPRSS4CES2CES1MEN1KMT2A | |
| SCHEMBL8175257 | 0.81 | CES2 (0.50) | TMPRSS4CES2CES1MEN1KMT2A | |
| SCHEMBL8174865 | 0.80 | CFTR (0.46) | CES2CES1HPGDKDM4EALDH1A1 | |
| SCHEMBL11644181 | 0.80 | TRPV1 (0.50) | TMPRSS4CES2CES1MEN1KMT2A | |
| SCHEMBL9851868 | 0.78 | CES2 (0.59) | CES2CES1HPGDPIK3CACYP1A2 | |
| SCHEMBL1760850 | 0.76 | CES2 (0.73) | CES2CES1HPGDALDH1A1ALOX15 | |
| SCHEMBL28188798 | 0.75 | GAA (0.57) | CES2CES1HPGDKDM4EALDH1A1 | |
| SCHEMBL11641986 | 0.74 | TMPRSS4 (0.53) | TMPRSS4CES2MEN1KMT2AP2RX1 | |
| SCHEMBL8183026 | 0.74 | CES2 (0.53) | CES2CES1HPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000063176-A2 | DISUBSTITUTED PYRIDINES AND PYRIMIDINES AS HERBICIDES AND FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-10-26 | — | — | WO | disclosed |