Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 3/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8182343 | 0.85 | CES2 (0.59) | TMPRSS4P2RX1CES2CES1KDM4E | |
| SCHEMBL11644181 | 0.83 | TRPV1 (0.50) | TMPRSS4P2RX1CES2CES1KDM4E | |
| SCHEMBL8179643 | 0.82 | TMPRSS4 (0.49) | TMPRSS4P2RX1CES2CES1KDM4E | |
| SCHEMBL28188798 | 0.82 | GAA (0.57) | CES2CES1KDM4EHTTRXFP1 | |
| SCHEMBL8177263 | 0.80 | SCN8A (0.46) | CES2CES1KDM4EHTTRXFP1 | |
| SCHEMBL8182743 | 0.78 | TMPRSS4 (0.46) | TMPRSS4P2RX1KDM4EHTTALDH1A1 | |
| SCHEMBL13291390 | 0.78 | CES2 (0.74) | CES2CES1HTTKMT2AL3MBTL1 | |
| SCHEMBL8175776 | 0.78 | CES2 (0.46) | TMPRSS4P2RX1CES2CES1HTT | |
| SCHEMBL8175748 | 0.76 | CES2 (0.47) | TMPRSS4P2RX1CES2CES1KDM4E | |
| SCHEMBL130628 | 0.73 | ALDH1A1 (0.59) | TMPRSS4CES2KDM4EHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000063176-A2 | DISUBSTITUTED PYRIDINES AND PYRIMIDINES AS HERBICIDES AND FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-10-26 | — | — | WO | disclosed |