Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473056 | 0.81 | ALDH1A1 (0.57) | ALDH1A1KDM4ESMN1; SMN2HTR7HTR1A | |
| SCHEMBL8179967 | 0.80 | ALDH1A1 (0.49) | ALDH1A1KDM4ESMN1; SMN2HTR7HTR1A | |
| SCHEMBL8195860 | 0.79 | ALDH1A1 (0.59) | ALDH1A1KDM4ESMN1; SMN2HTR7HTR1A | |
| SCHEMBL8195865 | 0.79 | ALDH1A1 (0.59) | ALDH1A1KDM4ESMN1; SMN2HTR7HTR1A | |
| SCHEMBL8194975 | 0.79 | ALDH1A1 (0.54) | ALDH1A1KDM4ESMN1; SMN2HTR7HTR1A | |
| SCHEMBL7466060 | 0.75 | ALDH1A1 (0.53) | ALDH1A1KDM4ESMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL7819243 | 0.73 | ALDH1A1 (0.60) | ALDH1A1KDM4ESMN1; SMN2HTR7HTR1A | |
| SCHEMBL8196728 | 0.73 | SLC6A1 (0.63) | ALDH1A1KDM4ESMN1; SMN2HTR7HTR1A | |
| SCHEMBL8196471 | 0.73 | SLC6A1 (0.63) | ALDH1A1KDM4ESMN1; SMN2HTR7HTR1A | |
| SCHEMBL8187340 | 0.72 | SLC6A1 (0.59) | ALDH1A1KDM4ESMN1; SMN2HTR7HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017915-A | Heterocyclic compounds | NOVO NORDISK A/S (DK) | 2000-01-25 | — | — | US | disclosed |