SCHEMBL818029

SCHEMBL818029

Fc1cc(-c2c(F)c(F)c(F)c(F)c2F)c(F)c(F)c1F.Fc1cc(-c2c(F)c(F)c(F)c(F)c2F)c(F)c(F)c1F.Fc1cc(-c2c(F)c(F)c(F)c(F)c2F)c(F)c(F)c1F.Fc1cc(-c2c(F)c(F)c(F)c(F)c2F)c(F)c(F)c1F.[O-]B([O-])[O-].c1ccc([C+](c2ccccc2)c2ccccc2)cc1.c1ccc([C+](c2ccccc2)c2ccccc2)cc1.c1ccc([C+](c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KCNQ3 O43525 1/20 0.30
KCNQ2 O43526 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7082376 0.94
SCHEMBL3125569 0.82
SCHEMBL215323 0.82
SCHEMBL7072934 0.77
SCHEMBL31177540 0.77
SCHEMBL5804582 0.74
SCHEMBL818997 0.74 CES2 (0.31)
SCHEMBL31001034 0.74 CES2 (0.31)
SCHEMBL6473935 0.72
SCHEMBL6473937 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3480031-A1 POLYMER BLEND Trinseo Europe GmbH (CH) 2019-05-08 EP disclosed
US-10253117-B2 Process for producing diene polymers TRINSEO EUROPE GMBH (CH) 2019-04-09 US disclosed
US-20180037682-A1 PROCESS FOR PRODUCING DIENE POLYMERS TRINSEO EUROPE GMBH (CH) 2018-02-08 US disclosed
US-9822195-B2 Process for producing diene polymers TRINSEO EUROPE GMBH (CH) 2017-11-21 US disclosed
EP-2819853-B1 PROCESS FOR PRODUCING DIENE POLYMERS TRINSEO EUROPE GMBH (CH) 2015-11-18 EP disclosed
US-20150210791-A1 Process for Producing Diene Polymers STYRON EUROPE GMBH (CH) 2015-07-30 US disclosed
EP-2267046-B1 Process for homo- or copolymerization of conjugated olefines STYRON EUROPE GMBH (CH) 2013-08-07 EP disclosed
US-8153545-B2 Process for homo—or copolymerization of conjugated olefins STYRON EUROPE GMBH (CH) 2012-04-10 US disclosed
US-20110160041-A1 PROCESS FOR HOMO - OR COPOLYMERIZATION OF CONJUGATED OLEFINS STYRON EUROPE GMBH 2011-06-30 US disclosed
US-7915194-B2 Process for homo- or copolymerization of conjugated olefins STYRON EUROPE GMBH (CH) 2011-03-29 US disclosed
US-20040241251-A1 Random or block co-or terpolymers produced by using of metal complex catalysts THIELE SVEN K H (DE) 2004-12-02 US disclosed
WO-2004076504-A2 PROCESS FOR HOMO- OR COPOLYMERIZATION OF CONJUGATED OLEFINES DOW GLOBAL TECHNOLOGIES, INC. (US) 2004-09-10 WO disclosed
WO-2004074333-A2 PROCESS FOR HOMO- OR COPOLYMERIZATIONOF CONJUGATED OLEFINES DOW GLOBAL TECHNOLOGIES INC. (US) 2004-09-02 WO disclosed
EP-1436332-A2 METAL COMPLEX COMPOSITIONS AND THEIR USE AS CATALYSTS TO PRODUCE POLYDIENES DOW GLOBAL TECHNOLOGIES INC. (US) 2004-07-14 EP disclosed
WO-2004044018-A2 PROCESS FOR HOMO- OR COPOLYMERIZATION OF CONJUGATED DIENES AND IN SITU FORMATION OF POLYMER BLENDS AND PRODUCTS MADE THEREBY DOW GLOBAL TECHNOLOGIES, INC. (US) 2004-05-27 WO disclosed
EP-1401879-A1 RANDOM OR BLOCK CO-OR TERPOLYMERS PRODUCED BY USING OF METAL COMPLEX CATALYSTS DOW GLOBAL TECHNOLOGIES INC. (US) 2004-03-31 EP disclosed
EP-1367069-A1 Process for homo-or copolymerization of conjugated diens DOW GLOBAL TECHNOLOGIES INC. (US) 2003-12-03 EP disclosed
WO-2003064484-A1 METAL COMPLEX COMPOSITIONS BASED ON COBALT AND THEIR USE AS POLYMERIZATION CATALYST FOR OLEFINS AND DIENES DOW GLOBAL TECHNOLOGIES INC. (US) 2003-08-07 WO disclosed
WO-2003033545-A2 METAL COMPLEX COMPOSITIONS AND THEIR USE AS CATALYSTS TO PRODUCE POLYDIENES DOW GLOBAL TECHNOLOGIES INC. (US) 2003-04-24 WO disclosed
WO-2002090394-A1 RANDOM OR BLOCK CO-OR TERPOLYMERS PRODUCED BY USING OF METAL COMPLEX CATALYSTS DOW GLOBAL TECHNOLOGIES INC. (US) 2002-11-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040241251-A1 Random or block co-or terpolymers produced by using of metal complex catalysts SQLE, AP1M1, COASY KCNQ3 4618/4885KCNQ2 4583/4885
US-20110160041-A1 PROCESS FOR HOMO - OR COPOLYMERIZATION OF CONJUGATED OLEFINS F12, ETFB, F2 KCNQ3 3968/4885KCNQ2 3402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.