Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.42 |
| ▸ | APP | P05067 | 8/20 | 0.42 |
| ▸ | BCHE | P06276 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8181858 | 0.93 | PDE5A (0.44) | — | |
| Bicarbonate SCHEMBL7013300 | 0.91 | ACHE (0.42) | ACHEAPPBCHEALDH1A1LMNA | |
| SCHEMBL8178313 | 0.88 | ACHE (0.44) | ACHEAPPBCHEMEN1KMT2A | |
| SCHEMBL8179512 | 0.87 | APP (0.44) | ACHEAPPBCHELMNAMAPT | |
| SCHEMBL8179646 | 0.86 | PDE5A (0.44) | ACHEALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL8178519 | 0.86 | PDE5A (0.45) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8169908 | 0.86 | PDE4B (0.38) | ALDH1A1LMNA | |
| SCHEMBL8180974 | 0.86 | ACHE (0.43) | ACHEAPPBCHEALDH1A1MEN1 | |
| SCHEMBL8171008 | 0.86 | ATG4B (0.38) | ALDH1A1 | |
| SCHEMBL8181251 | 0.86 | PDE4A (0.46) | ACHEAPPBCHEALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130223-A | Thienopyrimidine with phosphodiesterase V inhibiting effect | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-10-10 | — | — | US | disclosed |