Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.52 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | YWHAH | Q04917 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8171613 | 0.94 | PPARG (0.50) | PPARGS1PR3PTGER4PLA2G2APTGES2 | |
| SCHEMBL8165177 | 0.93 | PPARG (0.47) | PPARGS1PR3FOLH1F10PTGER4 | |
| SCHEMBL13931394 | 0.90 | PPARG (0.52) | PPARGS1PR3FOLH1F10PTGER4 | |
| SCHEMBL13931390 | 0.84 | PPARG (0.50) | PPARGPTGER4PLA2G2APTGES2KLKB1 | |
| SCHEMBL8167666 | 0.84 | POLB (0.58) | PPARGS1PR3FOLH1F10PTGER4 | |
| SCHEMBL4261606 | 0.84 | S1PR3 (0.52) | PPARGS1PR3FOLH1F10PTGER4 | |
| SCHEMBL8167668 | 0.84 | PLA2G1B (0.43) | PPARGFOLH1YWHAHPLA2G2A | |
| SCHEMBL13931389 | 0.83 | PLA2G2A (0.49) | PPARGS1PR3FOLH1F10PTGER4 | |
| SCHEMBL8174763 | 0.82 | KMT2A (0.43) | PPARGPTGER4 | |
| SCHEMBL8167328 | 0.80 | MEN1 (0.52) | PPARGS1PR3FOLH1PTGER4PTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008100867-A2 | NOVEL INHIBITORS HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2008-08-21 | — | — | WO | disclosed |