Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13931396 | 0.89 | PLA2G2A (0.48) | PLA2G1BPLA2G2APPARGMEN1KMT2A | |
| SCHEMBL8171635 | 0.88 | MEN1 (0.53) | PLA2G2AMEN1KMT2AFAAHMAPT | |
| SCHEMBL8165177 | 0.88 | PPARG (0.47) | PLA2G1BPLA2G2APPARGMEN1KMT2A | |
| SCHEMBL8171613 | 0.86 | PPARG (0.50) | PLA2G2APPARGTHRATHRB | |
| SCHEMBL8181548 | 0.84 | PPARG (0.40) | PLA2G1BPLA2G2APPARGMEN1KMT2A | |
| SCHEMBL8165192 | 0.84 | MEN1 (0.53) | MEN1KMT2APTGESALOX5MAPT | |
| SCHEMBL8180895 | 0.84 | PPARG (0.52) | PLA2G2APPARGYWHAHFOLH1 | |
| SCHEMBL8165198 | 0.83 | FOLH1 (0.48) | MEN1KMT2AMAPTGFERALDH1A1 | |
| SCHEMBL8174763 | 0.80 | KMT2A (0.43) | PPARGKMT2AMAPTTSHRPTGDR2 | |
| SCHEMBL8175786 | 0.80 | KMT2A (0.41) | PLA2G1BPLA2G2AMEN1KMT2APTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008100867-A2 | NOVEL INHIBITORS HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2008-08-21 | — | — | WO | disclosed |