Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 8/20 | 0.54 |
| ▸ | PYGL | P06737 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | GUSB | P08236 | 2/20 | 0.42 |
| ▸ | UGCG | Q16739 | 2/20 | 0.42 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8187378 | 1.00 | GBA1 (0.54) | GBA1PYGLBCHEACHEKCNH2 | |
| SCHEMBL8185201 | 0.95 | PYGL (0.54) | GBA1PYGLBCHEACHE | |
| SCHEMBL8176411 | 0.87 | PYGL (0.69) | GBA1PYGLKCNH2GAA | |
| SCHEMBL8172188 | 0.86 | GBA1 (0.58) | GBA1PYGLUGCGGBA2GAA | |
| SCHEMBL403643 | 0.82 | GBA1 (0.66) | GBA1PYGL | |
| SCHEMBL2454394 | 0.82 | GBA1 (0.66) | GBA1PYGL | |
| SCHEMBL440211 | 0.82 | GBA1 (0.66) | GBA1PYGL | |
| SCHEMBL8181071 | 0.81 | PYGL (0.49) | GBA1PYGLUGCGGBA2 | |
| SCHEMBL8187072 | 0.80 | GBA1 (0.47) | GBA1PYGLUGCGGBA2GAA | |
| SCHEMBL14388983 | 0.79 | GBA1 (0.59) | GBA1PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983239-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998050359-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-11-12 | — | — | WO | disclosed |