SCHEMBL818115

SCHEMBL818115

CCc1cc(Cc2cc(Cl)c(N)c(CC)c2)cc(Cl)c1N

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.42
HTT P42858 2/20 0.38
POLB P06746 1/20 0.38
CSNK2A2 P19784 1/20 0.38
CSNK2B P67870 1/20 0.38
CSNK2A1 P68400 1/20 0.38
CSNK2A3 Q8NEV1 1/20 0.38
DHFR P00374 3/20 0.37
ALDH1A1 P00352 3/20 0.36
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2A Q12879 1/20 0.33
GRIN2B Q13224 1/20 0.33
GRIN2C Q14957 1/20 0.33
GRIN3A Q8TCU5 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30806157 1.00 CYP3A4 (0.42) CYP3A4HTTPOLBCSNK2A2CSNK2B
SCHEMBL10355610 0.98 HTT (0.41) CYP3A4HTTPOLBCSNK2A2CSNK2B
SCHEMBL5839871 0.98 HTT (0.41) CYP3A4HTTPOLBCSNK2A2CSNK2B
SCHEMBL13804214 0.89 HTT (0.39) CYP3A4HTTPOLBCSNK2A2CSNK2B
SCHEMBL48459 0.84 HTT (0.50) HTTPOLBDHFRALDH1A1MAPT
SCHEMBL940822 0.79 ALDH1A1 (0.55) CYP3A4HTTPOLBALDH1A1CA1
SCHEMBL28283125 0.78 HTT (0.41) CYP3A4HTTPOLBCSNK2A2CSNK2B
SCHEMBL205507 0.78 HTT (0.41) CYP3A4HTTPOLBALDH1A1CA1
SCHEMBL29395088 0.77 ALDH1A1 (0.49) CYP3A4HTTPOLBDHFRALDH1A1
SCHEMBL48397 0.77 ALDH1A1 (0.49) CYP3A4HTTPOLBDHFRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 426 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250250460-A1 COATING KIT AND METHOD FOR REPAIR AND/OR RECONSTITUTION OF RUBBER AND/OR METAL WORN AREAS BERTECH PANAMA S.A. (PA) 2025-08-07 US claimed
EP-2513181-B1 COATING COMPOSITION ALBEMARLE CORP (US) 2016-08-17 EP claimed
US-8871891-B2 Two part polyurea-urethane adhesive with elevated high temperature storage modulus ASHLAND LICENSING AND INTELLECTUAL PROPERTY LLC (US) 2014-10-28 US claimed
EP-2709842-A2 TWO PART POLYUREA-URETHANE ADHESIVE WITH ELEVATED HIGH TEMPERATURE STORAGE MODULUS Ashland, Inc. (US) 2014-03-26 EP claimed
US-8536297-B2 Coating composition ALBEMARLE CORPORATION (US) 2013-09-17 US claimed
US-20120295104-A1 Two Part Polyurea-Urethane Adhesive with Elevated High Temperature Storage Modulus ARKEMA FRANCE (FR) 2012-11-22 US claimed
WO-2012158664-A2 TWO PART POLYUREA-URETHANE ADHESIVE WITH ELEVATED HIGH TEMPERATURE STORAGE MODULUS ASHLAND INC. (US) 2012-11-22 WO claimed
EP-2513181-A1 COATING COMPOSITION Albemarle Corporation (US) 2012-10-24 EP claimed
US-20120252971-A1 Coating Composition ALBEMARLE CORPORATION (US) 2012-10-04 US claimed
WO-2011084602-A1 COATING COMPOSITION ALBEMARLE CORPORATION (US) 2011-07-14 WO claimed
EP-1033380-B1 Polyurethaneurea elastomers for dynamic applications AIR PROD & CHEM (US) 2006-05-10 EP claimed
EP-1033380-A1 Polyurethaneurea elastomers for dynamic applications AIR PRODUCTS AND CHEMICALS, INC. (US) 2000-09-06 EP claimed
US-6114488-A Polyurethaneurea elastomers for dynamic applications AIR PRODUCTS AND CHEMICALS, INC. (US) 2000-09-05 US claimed
EP-0579989-B1 Polyurethaneurea elastomer IHARA CHEMICAL IND CO (JP) 1997-09-03 EP claimed
US-5410009-A Impact resilience; flexural properties IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1995-04-25 US claimed
EP-0579989-A1 Polyurethaneurea elastomer IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) 1994-01-26 EP claimed
EP-0538694-A2 Polyurea or polyurea-urethane adhesive for bonding elastomers H.B. FULLER LICENSING & FINANCING, INC. (US) 1993-04-28 EP claimed
US-5183877-A For retread tires H. B. FULLER COMPANY (US) 1993-02-02 US claimed
US-5039775-A Process for producing polyurea resin IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1991-08-13 US claimed
EP-0171588-B1 CHAIN-LENGTHENING OR CROSS-LINKING AGENT LONZA AG (CH) 1990-09-26 EP claimed