SCHEMBL48459

SCHEMBL48459

CCc1cc(Cc2cc(CC)c(N)c(CC)c2)cc(CC)c1N

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.50
POLB P06746 1/20 0.50
DHFR P00374 6/20 0.42
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37
BACE1 P56817 1/20 0.36
NOS3 P29474 1/20 0.35
NOS1 P29475 1/20 0.35
NOS2 P35228 1/20 0.35
SHBG P04278 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28301882 0.91 HTT (0.44) HTTPOLBDHFRALDH1A1MAPT
SCHEMBL3946139 0.89 ALDH1A1 (0.43) HTTPOLBDHFRALDH1A1MAPT
SCHEMBL14068526 0.89 ALDH1A1 (0.47) HTTPOLBDHFRALDH1A1MAPT
SCHEMBL5610844 0.89 DHFR (0.44) HTTPOLBDHFRALDH1A1MAPT
SCHEMBL5380950 0.89 DHFR (0.44) HTTPOLBDHFRBACE1
SCHEMBL10355610 0.87 HTT (0.41) HTTPOLBDHFRALDH1A1MAPT
SCHEMBL5839871 0.87 HTT (0.41) HTTPOLBDHFRALDH1A1MAPT
SCHEMBL9456455 0.87 CALM1 (0.48) HTTPOLB
SCHEMBL10508727 0.87 CYP3A4 (0.56) HTTPOLBDHFRALDH1A1BACE1
SCHEMBL112571 0.86 HTT (0.52) HTTPOLBDHFRALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6390 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4098400-B1 POLISHING PAD AND METHOD FOR PREPARING A SEMICONDUCTOR DEVICE USING THE SAME ENPULSE CO LTD (KR) 2026-04-22 EP claimed
US-20260091462-A1 PAD FOR CHEMICAL MECHANICAL POLISHING DUPONT ELECTRONIC MAT HOLDING INC (US) 2026-04-02 US claimed
US-12570029-B2 Method for manufacturing polishing pad window, and polishing pad window manufactured thereby KPX Chemical Co., Ltd (KR) 2026-03-10 US claimed
CN-121575594-A Urethane adhesive cord treatment and tape for electric power transmission tape 盖茨公司 2026-02-27 CN claimed
EP-4676995-A1 CURABLE MASS, METHOD FOR JOINING, CASTING AND COATING SUBSTRATES AND USE OF THE MASS DELO Industrie Klebstoffe GmbH & Co. KGaA (DE) 2026-01-14 EP claimed
US-12515295-B2 Polishing pad and method for preparing a semiconductor device using the same ENPULSE CO., LTD. (KR) 2026-01-06 US claimed
US-12503546-B2 Curable polyurethane prepolymer composition URETHANE SYSTEMS USA LLC (US) 2025-12-23 US claimed
US-12460043-B2 Epoxy resin composition for fiber-reinforced composite material, prepreg, and fiber-reinforced composite material THE YOKOHAMA RUBBER CO., LTD. (JP) 2025-11-04 US claimed
US-20250333579-A1 COMPOSITION AND PACKAGE STRUCTURE INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2025-10-30 US claimed
US-12378351-B2 Polyurethane belt with improved hydrolysis resistance GATES CORPORATION (US) 2025-08-05 US claimed
US-4820743-A BLEND OF POLYETHERPOLYOL AND POLYAMINE, AND UNSATURATED MONOMER SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1989-04-11 US claimed
EP-0173888-A1 A process for the production of polyurethane elastomers and an isocyanate-reactive composition to be used in this process MOBAY CORPORATION (US) 1986-03-12 EP claimed
US-4530941-A Replacing a portion of polyol with an oxyalkylene compound containing amine groups THE DOW CHEMICAL COMPANY (US) 1985-07-23 US claimed
US-4519965-A ZINC CARBOXYLATE AND NITROGEN CONTAINING ACYCLIC COMPOUND MOBAY CHEMICAL CORPORATION (US) 1985-05-28 US claimed
US-4379105-A Process for the production of elastic shaped articles MOBAY CHEMICAL CORPORATION (US) 1983-04-05 US claimed
EP-0044481-A1 Process for the production of elastomeric moulded products Mobay Chemical Corporation (US) 1982-01-27 EP claimed
US-4289906-A Chemical process for preparing methylene bis-anilines ETHYL CORPORATION (US) 1981-09-15 US claimed
EP-0033498-A1 A process for preparing reaction injection molded polyurethane compositions employing aliphatic amine chain extenders THE DOW CHEMICAL COMPANY (US) 1981-08-12 EP claimed
US-4269945-A USING A POLYOXYPROPYLENE GLYCOL ENDCAPPED WITH AN AMINO-CONTAINING ALCOHOL ALONG WITH A POLYHYDROXY COMPOUND, AND AROMATIC POLYAMINE; POLYETHERURETHANES THE DOW CHEMICAL COMPANY (US) 1981-05-26 US claimed
US-4218543-A REACTION INJECTION MOLDING BAYER AKTIENGESELLSCHAFT (DE) 1980-08-19 US claimed