Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.38 |
| ▸ | CCR8 | P51685 | 2/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 10/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | ALPI | P09923 | 1/20 | 0.31 |
| ▸ | ALPG | P10696 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PGK1 | P00558 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13400154 | 1.00 | CCR1 (0.38) | CCR1CCR8IRAK4ADRB1SCN9A | |
| SCHEMBL12786233 | 0.87 | MEN1 (0.50) | IRAK4SCN9ACNR1CNR2 | |
| SCHEMBL2304288 | 0.87 | MEN1 (0.50) | IRAK4SCN9ACNR1CNR2 | |
| SCHEMBL6650361 | 0.84 | ALDH1A1 (0.56) | IRAK4SCN9A | |
| SCHEMBL13400149 | 0.82 | HTT (0.42) | CCR1CCR8IRAK4ADRB1SMN1; SMN2 | |
| SCHEMBL14124549 | 0.80 | IRAK4 (0.39) | IRAK4ADRB1 | |
| SCHEMBL6648424 | 0.80 | IRAK4 (0.39) | IRAK4ADRB1 | |
| SCHEMBL6648617 | 0.76 | SCN9A (0.47) | SCN9ASMN1; SMN2 | |
| SCHEMBL6673866 | 0.74 | ALDH1A1 (0.44) | IRAK4SCN9ACNR1CNR2 | |
| SCHEMBL12786394 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906651-B2 | Catalytic system of asymmetric reactions in aqueous media; react a silicon enolate and formaldehyde; catalyst obtained by mixing chiral ligands with scandium triflate | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-03-15 | — | — | US | disclosed |
| US-7906651-B2 | Catalytic system of asymmetric reactions in aqueous media; react a silicon enolate and formaldehyde; catalyst obtained by mixing chiral ligands with scandium triflate | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-03-15 | — | — | US | disclosed |
| US-7541307-B2 | Method for manufacturing an optically active hydroxymethylated compound and a catalyst therefore | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2009-06-02 | — | — | US | disclosed |
| US-7541307-B2 | Method for manufacturing an optically active hydroxymethylated compound and a catalyst therefore | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2009-06-02 | — | — | US | disclosed |
| US-20080269496-A1 | Method for Producing Optically Active Hydroxymethylated Compounds | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-10-30 | — | — | US | disclosed |
| US-20080269496-A1 | Method for Producing Optically Active Hydroxymethylated Compounds | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-10-30 | — | — | US | disclosed |
| US-20080139835-A1 | Method for Manufacturing an Optically Active Hydroxymethylated Compound and a Catalyst Therefore | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-06-12 | — | — | US | disclosed |
| US-20080139835-A1 | Method for Manufacturing an Optically Active Hydroxymethylated Compound and a Catalyst Therefore | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-06-12 | — | — | US | disclosed |
| EP-1852412-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE HYDROXYMETHYLATED COMPOUNDS AND CATALYST THEREFOR | Japan Science and Technology Agency (JP) | 2007-11-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139835-A1 | Method for Manufacturing an Optically Active Hydroxymethylated Compound and a Catalyst Therefore | OGFOD1, POF1B, EEF1D | CCR1 1966/4885CCR8 2904/4885IRAK4 4506/4885 |
| US-20080269496-A1 | Method for Producing Optically Active Hydroxymethylated Compounds | TET1, TET3, CYP3A4 | CCR1 4624/4885CCR8 4703/4885IRAK4 3943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.