Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | DDO | Q99489 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8183051 | 0.73 | ALDH1A1 (0.49) | CA2CYP1A2CYP2D6PTGER3HSD17B10 | |
| SCHEMBL8186819 | 0.71 | AR (0.39) | CA2SMN1; SMN2CYP1A2HIF1APTGER3 | |
| SCHEMBL8182940 | 0.69 | MAOB (0.54) | CA2SMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL8189523 | 0.68 | HTR2A (0.41) | CA2RAB9ACYP3A4CYP1A2HIF1A | |
| SCHEMBL8210168 | 0.67 | CA2 (0.39) | CA2PTGER3DAO | |
| SCHEMBL8172477 | 0.67 | TSHR (0.42) | TP53ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL8182984 | 0.66 | KDM4E (0.50) | TP53SMN1; SMN2HSD17B10ALDH1A1HPGD | |
| SCHEMBL8188584 | 0.66 | NQO1 (0.35) | HSD17B10ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL8181635 | 0.66 | CA2 (0.41) | CA2BRD4MEN1KMT2ADAO | |
| SCHEMBL12746661 | 0.66 | CA2 (0.41) | CA2BRD4CYP3A4CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018745-A1 | OXAZOLIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF METABOLIC BONE DISORDERS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |