Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 13/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL817092 | 1.00 | VDR (0.51) | VDR | |
| SCHEMBL817138 | 0.93 | VDR (0.50) | VDR | |
| SCHEMBL817144 | 0.93 | VDR (0.50) | VDR | |
| SCHEMBL823016 | 0.91 | VDR (0.47) | VDR | |
| SCHEMBL822900 | 0.91 | VDR (0.47) | VDR | |
| SCHEMBL9010767 | 0.90 | VDR (0.58) | VDR | |
| SCHEMBL13243997 | 0.86 | VDR (0.40) | VDR | |
| SCHEMBL14112577 | 0.86 | VDR (0.54) | VDR | |
| SCHEMBL14489228 | 0.86 | VDR (0.54) | VDR | |
| SCHEMBL10820227 | 0.86 | VDR (0.54) | VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8058265-B2 | 1a-hydroxy-2-(3'-hydroxypropylidene)-19-nor-vitamin D compounds and methods of making and treatment thereof | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2011-11-15 | — | — | US | disclosed |
| US-20090281340-A1 | 1ALPHA-HYDROXY-2-(3'-HYDROXYPROPYLIDENE)-19-NOR-VITAMIN D COMPOUNDS AND METHODS OF MAKING AND TREATMENT THEREOF | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2009-11-12 | — | — | US | disclosed |
| US-20070244072-A1 | 1a-Hydroxy-2-(3'-Hydroxypropylidene)-19-nor-vitamin D compounds and methods of making and treatment thereof | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244072-A1 | 1a-Hydroxy-2-(3'-Hydroxypropylidene)-19-nor-vitamin D compounds and methods of making and treatment thereof | CYP24A1, CYP2R1, VDR | VDR 3/4885 |
| US-20090281340-A1 | 1ALPHA-HYDROXY-2-(3'-HYDROXYPROPYLIDENE)-19-NOR-VITAMIN D COMPOUNDS AND METHODS OF MAKING AND TREATMENT THEREOF | CYP24A1, CYP2R1, VDR | VDR 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.