Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8179692 | 0.84 | MAPT (0.32) | KMT2AMAPTGRM2MAOBALDH1A1 | |
| SCHEMBL8182974 | 0.81 | P2RY12 (0.50) | P2RY12KMT2AMAPTMEN1CASP3 | |
| SCHEMBL8185683 | 0.79 | KMT2A (0.48) | P2RY12KMT2AMAPTMEN1CASP3 | |
| SCHEMBL8190118 | 0.77 | HDAC1 (0.40) | SMN1; SMN2 | |
| SCHEMBL8184534 | 0.76 | ALDH1A1 (0.38) | P2RY12KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL8179579 | 0.75 | CHRNA7 (0.46) | P2RY12KMT2AMAPTMEN1CASP3 | |
| SCHEMBL8173673 | 0.75 | CYP2C9 (0.39) | KMT2AMAPTMEN1MAOBALDH1A1 | |
| SCHEMBL8184805 | 0.72 | SYK (0.36) | P2RY12MAOBPDPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13428802 | 0.69 | P2RY12 (0.59) | P2RY12MAPTALDH1A1KDM4EPOLB | |
| SCHEMBL8187389 | 0.69 | ALDH1A1 (0.52) | P2RY12KMT2AMAPTMEN1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008075757-A1 | N-HYDROXYACRYLAMIDE COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2008-06-26 | — | — | WO | disclosed |