Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8182974 | 0.90 | P2RY12 (0.50) | KMT2AMEN1MAPTPOLBLMNA | |
| SCHEMBL13428812 | 0.89 | P2RY12 (0.51) | KMT2AMEN1MAPTPOLBLMNA | |
| SCHEMBL8179128 | 0.81 | HPGD (0.44) | KMT2APOLBLMNAHPGDF2 | |
| SCHEMBL8182256 | 0.79 | P2RY12 (0.40) | KMT2AMEN1MAPTPOLBHPGD | |
| SCHEMBL8179579 | 0.79 | CHRNA7 (0.46) | KMT2AMEN1MAPTHPGDP2RY12 | |
| SCHEMBL13428802 | 0.78 | P2RY12 (0.59) | MAPTPOLBLMNAHPGDP2RY12 | |
| SCHEMBL31141621 | 0.77 | MEN1 (0.57) | KMT2AMEN1MAPTPOLBLMNA | |
| SCHEMBL8187060 | 0.75 | HDAC1 (0.52) | KMT2AMAPTPOLBLMNAL3MBTL1 | |
| SCHEMBL8187389 | 0.72 | ALDH1A1 (0.52) | KMT2AMEN1MAPTHPGDP2RY12 | |
| SCHEMBL13428528 | 0.72 | LMNA (0.44) | KMT2ALMNAHPGDALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008075757-A1 | N-HYDROXYACRYLAMIDE COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2008-06-26 | — | — | WO | disclosed |