Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA7 | P43166 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL818271 | 0.85 | TSHR (0.40) | CYP1A2TSHRMAPK1ALDH1A1HPGD | |
| SCHEMBL818988 | 0.84 | ALDH1A1 (0.43) | TSHRMAPK1ALDH1A1MAPTESR1 | |
| SCHEMBL817874 | 0.81 | TSHR (0.37) | CYP1A2TSHRGAACA12CA1 | |
| SCHEMBL819817 | 0.77 | TSHR (0.36) | CYP1A2TSHRGAACA12CA1 | |
| Hydrochloric Acid SCHEMBL28431908 | 0.72 | TSHR (0.33) | TSHRGAAALDH1A1HPGDMAPT | |
| SCHEMBL16349333 | 0.70 | LMNA (0.42) | CYP1A2TSHRGAACA12CA1 | |
| SCHEMBL817737 | 0.68 | ALDH1A1 (0.38) | TSHRGAAALDH1A1HPGDMAPT | |
| SCHEMBL818264 | 0.67 | ALDH1A1 (0.40) | TSHRMAPK1ALDH1A1HPGDMAPT | |
| Hydrochloric Acid SCHEMBL28896140 | 0.67 | TSHR (0.32) | TSHRGAAALDH1A1HPGDMAPT | |
| SCHEMBL18382542 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236908-B2 | Components and catalysts for the polymerization of olefins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20110269927-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-03 | — | — | US | disclosed |