Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 5/20 | 0.62 |
| ▸ | PRKCG | P05129 | 5/20 | 0.62 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.62 |
| ▸ | PRKCB | P05771 | 4/20 | 0.62 |
| ▸ | PRKCH | P24723 | 4/20 | 0.62 |
| ▸ | PRKCI | P41743 | 4/20 | 0.62 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.62 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.62 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.62 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.62 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.62 |
| ▸ | VAV1 | P15498 | 2/20 | 0.62 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8191190 | 0.90 | PRKCA (0.62) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| SCHEMBL24401808 | 0.90 | PRKCA (0.65) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| SCHEMBL18628013 | 0.89 | PRKCA (0.64) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| SCHEMBL2410030 | 0.89 | PRKCA (0.64) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| SCHEMBL21226899 | 0.89 | PRKCA (0.64) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| SCHEMBL15423113 | 0.89 | PRKCA (0.64) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| SCHEMBL18873261 | 0.89 | PRKCA (0.59) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| SCHEMBL16922843 | 0.89 | PRKCA (0.64) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| SCHEMBL8189840 | 0.89 | PRKCA (0.63) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL15976176 | 0.88 | PRKCA (0.60) | PRKCAPRKCGPRKD3PRKCBPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080784-A | Protein kinase C modulators N | PROCYON PHARMACEUTICALS, INC. (US) | 2000-06-27 | — | — | US | claimed |
| US-5955501-A | DERIVED FROM PHORBOIDS OF THE DITERPENE- AND BENZOLACTAM-CLASSES. | PROCYON PHARMACEUTICALS, INC. (US) | 1999-09-21 | — | — | US | claimed |
| WO-1996040614-A1 | PROTEIN KINASE C MODULATORS .X. | PROCYON PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | claimed |
| WO-1996040614-A1 | PROTEIN KINASE C MODULATORS .X. | PROCYON PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |