Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 5/20 | 0.64 |
| ▸ | PRKCG | P05129 | 5/20 | 0.64 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.64 |
| ▸ | PRKCB | P05771 | 4/20 | 0.64 |
| ▸ | PRKCH | P24723 | 4/20 | 0.64 |
| ▸ | PRKCI | P41743 | 4/20 | 0.64 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.64 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.64 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.64 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.64 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.64 |
| ▸ | VAV1 | P15498 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18628013 | 1.00 | PRKCA (0.64) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| SCHEMBL21226899 | 1.00 | PRKCA (0.64) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| SCHEMBL16922843 | 1.00 | PRKCA (0.64) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| SCHEMBL15423113 | 1.00 | PRKCA (0.64) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| SCHEMBL24401808 | 0.93 | PRKCA (0.65) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| SCHEMBL8189840 | 0.92 | PRKCA (0.63) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| SCHEMBL19331474 | 0.91 | PRKCA (0.71) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| SCHEMBL22171733 | 0.91 | PRKCA (0.56) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| SCHEMBL8183278 | 0.89 | PRKCA (0.62) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| SCHEMBL11125018 | 0.88 | PTGS2 (0.62) | PRKCAPRKCGPRKD3PRKCBPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260041660-A1 | Compositions And Methods for Treating Acute Respiratory Distress Syndrome (ARDS) And Inflammatory Disorders Caused by Corona Viruses and Other Respiratory Pathogens or Agents That Mediate Pulmonary Injury, Inflammation or Acute Respiratory Distress, And Related Compositions and Methods for Treating and Preventing Human SARS Coronavirus Infection, COVID-19 Disease and Related Symptoms | CHANG RICHARD L (US) | 2026-02-12 | — | — | US | claimed |
| US-12539289-B2 | Phorbol ester compositions and methods of use for treating or reducing the duration of cytopenia | BIOSUCCESS BIOTECH COMPANY, LIMITED (US) | 2026-02-03 | — | — | US | claimed |
| EP-2804601-B1 | PHORBOL ESTER compounds for use in the treatment of neoplastic diseases | BIOSUCCESS BIOTECH CO LTD (US) | 2025-04-02 | — | — | EP | claimed |
| US-20240261247-A1 | COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS | BIOSUCCESS BIOTECH CO., LTD. (US) | 2024-08-08 | — | — | US | claimed |
| US-20240082202-A1 | Compositions And Methods for Treating Acute Respiratory Distress Syndrome (ARDS) And Inflammatory Disorders Caused by Corona Viruses and Other Respiratory Pathogens or Agents That Mediate Pulmonary Injury, Inflammation or Acute Respiratory Distress, And Related Compositions and Methods for Treating and Preventing Human SARS Coronavirus Infection, COVID-19 Disease and Related Symptoms | CHANG RICHARD L (US) | 2024-03-14 | — | — | US | claimed |
| EP-4304570-A2 | COMPOSITIONS AND METHODS FOR TREATING ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) AND INFLAMMATORY DISORDERS CAUSED BY CORONAVIRUSES | Phor-Med, Inc. (US) | 2024-01-17 | — | — | EP | claimed |
| CN-117015375-A | Compositions and methods for treating Acute Respiratory Distress Syndrome (ARDS) and inflammatory conditions caused by coronaviruses | 福尔医学公司 | 2023-11-07 | — | — | CN | claimed |
| US-20230277495-A1 | COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS | BIOSUCCESS BIOTECH CO. LTD. (US) | 2023-09-07 | — | — | US | claimed |
| US-20230248684-A1 | COMPOSITIONS AND METHODS FOR TREATING ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) AND INFLAMMATORY DISORDERS CAUSED BY CORONAVIRUSES AND OTHER RESPIRATORY PATHOGENS OR AGENTS THAT MEDIATE PULMONARY INJURY, INFLAMMATION OR ACUTE RESPIRATORY DISTRESS, AND RELATED COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING HUMAN SARS CORONAVIRUS INFECTION, COVID-19 DISEASE AND RELATED SYMPTOMS | PHOR-MED, INC. | 2023-08-10 | — | — | US | claimed |
| US-11696908-B2 | Compositions and methods of use of phorbol esters | BIOSUCCESS BIOTECH CO. LTD. (US) | 2023-07-11 | — | — | US | claimed |
| US-20140018329-A1 | COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS IN THE TREATMENT OF NEOPLASMS | BIOSUCCESS BIOTECH CO., LTD. (US) | 2014-01-16 | — | — | US | claimed |
| US-20140017196-A1 | COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS | BIOSUCCESS BIOTECH CO., LTD. (US) | 2014-01-16 | — | — | US | claimed |
| US-20140017194-A1 | Compositions And Methods Of Use Of Phorbol Esters | BIOSUCCESS BIOTECH CO. LTD. (US) | 2014-01-16 | — | — | US | claimed |
| WO-2014011209-A1 | COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS FOR THE TREATMENT OF STROKE | BIOSUCCESS BIOTECH CO. LTD. (US) | 2014-01-16 | — | — | WO | claimed |
| US-20140011873-A1 | COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS FOR THE TREATMENT OF STROKE | BIOSUCCESS BIOTECH CO., LTD (US) | 2014-01-09 | — | — | US | claimed |
| WO-2013110006-A2 | COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS | BIOSUCCESS BIOTECH CO. LTD. (US) | 2013-07-25 | — | — | WO | claimed |
| EP-2368555-A1 | Compositions and methods of use of phorbolesters | Biosuccess Biotech Company (US) | 2011-09-28 | — | — | EP | claimed |
| EP-2170053-A1 | COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS | Biosuccess Biotech Company (US) | 2010-04-07 | — | — | EP | claimed |
| US-20080226589-A1 | Such as phorbol 13-butyrate for treatment of cytopathic diseases such as HIV, AIDS, and/or neoplasms | BIOSUCCESS BIOTECH CO. | 2008-09-18 | — | — | US | claimed |
| WO-2008094657-A1 | COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS | BIOSUCCESS BIOTECH COMPANY (US) | 2008-08-07 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140011873-A1 | COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS FOR THE TREATMENT OF STROKE | PMAIP1, EBP, PLAT | PRKCA 13/4885PRKCG 18/4885PRKD3 460/4885 |
| US-11696908-B2 | Compositions and methods of use of phorbol esters | PMAIP1, CD38, PKD1 | PRKCA 41/4885PRKCG 53/4885PRKD3 229/4885 |
| US-20240261247-A1 | COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS | PMAIP1, KLK3, ACP3 | PRKCA 42/4885PRKCG 51/4885PRKD3 235/4885 |
| US-20230277495-A1 | COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS | PMAIP1, KLK3, ACP3 | PRKCA 42/4885PRKCG 51/4885PRKD3 235/4885 |
| US-20140018329-A1 | COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS IN THE TREATMENT OF NEOPLASMS | PMAIP1, MYD88, HRAS | PRKCA 15/4885PRKCG 33/4885PRKD3 206/4885 |
| US-20260041660-A1 | Compositions And Methods for Treating Acute Respiratory Distress Syndrome (ARDS) And Inflammatory Disorders Caused by Corona Viruses and Other Respiratory Pathogens or Agents That Mediate Pulmonary Injury, Inflammation or Acute Respiratory Distress, And Related Compositions and Methods for Treating and Preventing Human SARS Coronavirus Infection, COVID-19 Disease and Related Symptoms | TSLP, MAVS, PLAA | PRKCA 32/4885PRKCG 102/4885PRKD3 910/4885 |
| US-20080226589-A1 | Such as phorbol 13-butyrate for treatment of cytopathic diseases such as HIV, AIDS, and/or neoplasms | STAT6, NFATC1, BAD | PRKCA 164/4885PRKCG 366/4885PRKD3 138/4885 |
| US-12539289-B2 | Phorbol ester compositions and methods of use for treating or reducing the duration of cytopenia | MYD88, EBP, IL2 | PRKCA 45/4885PRKCG 154/4885PRKD3 274/4885 |
| US-20140017196-A1 | COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS | PMAIP1, CD38, PKD1 | PRKCA 41/4885PRKCG 53/4885PRKD3 229/4885 |
| US-20240082202-A1 | Compositions And Methods for Treating Acute Respiratory Distress Syndrome (ARDS) And Inflammatory Disorders Caused by Corona Viruses and Other Respiratory Pathogens or Agents That Mediate Pulmonary Injury, Inflammation or Acute Respiratory Distress, And Related Compositions and Methods for Treating and Preventing Human SARS Coronavirus Infection, COVID-19 Disease and Related Symptoms | MAVS, ACE2, PLAA | PRKCA 12/4885PRKCG 36/4885PRKD3 885/4885 |
| US-20230248684-A1 | COMPOSITIONS AND METHODS FOR TREATING ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) AND INFLAMMATORY DISORDERS CAUSED BY CORONAVIRUSES AND OTHER RESPIRATORY PATHOGENS OR AGENTS THAT MEDIATE PULMONARY INJURY, INFLAMMATION OR ACUTE RESPIRATORY DISTRESS, AND RELATED COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING HUMAN SARS CORONAVIRUS INFECTION, COVID-19 DISEASE AND RELATED SYMPTOMS | MAVS, ACE2, CCL11 | PRKCA 16/4885PRKCG 34/4885PRKD3 716/4885 |
| US-20140017194-A1 | Compositions And Methods Of Use Of Phorbol Esters | STAT6, NFATC1, PMAIP1 | PRKCA 54/4885PRKCG 153/4885PRKD3 218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.